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Low-frequency and rare genetic variants associated with rheumatoid arthritis risk
Rheumatoid arthritis has a substantial genetic component, some of which is associated with the presence of low-frequency or rare variants. Next-generation sequencing in large and well-defined cohorts can continue to identify these variants and thereby contribute to the future prediction, diagnosis and treatment of rheumatoid arthritis.
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25 years of biologic therapy
Biologic therapies with various modes of action have been introduced into the field of rheumatology over the past 25 years, and have revolutionized the treatment and outcomes in many rheumatic diseases. This collection from Nature Reviews Rheumatology brings together articles on biologic therapy in rheumatology, including the latest Reviews and Opinion pieces, as well as popular content from our archives.
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Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors
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Predominant ligament-centric soft-tissue involvement differentiates axial psoriatic arthritis from ankylosing spondylitis
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The clinical benefits of sodium–glucose cotransporter type 2 inhibitors in people with gout
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Evidence-Based Guideline for the management of osteoporosis in men