Jigsaw puzzle of a joint with pieces missing

Recent advancements in cartilage tissue engineering innovation and translation

  • Rachel C. Nordberg
  • Benjamin J. Bielajew
  • Kyriacos A. Athanasiou
Review Article


  • A crowd of people with two individuals highlighted in a different colour

    Keep up to date with changes to the conference calendar this year and find out which meetings will be attended by the editors of Nature Reviews Rheumatology.

  • Paper boats seen through a spyglass

    Finding it hard to navigate the flood of scientific literature? The Nature Reviews journals filter and highlight the most impactful research. Take a look at this animation to learn how Nature Reviews can help you stay up-to-date in your field

  • Knee x-ray of a 60 year old woman showing degenerative joint disease from osteoarthritis

    Osteoarthritis (OA) is a degenerative joint disease that leads to pain, stiffness and loss of function. It is the most common form of arthritis and one of the most prevalent musculoskeletal disorders worldwide. This collection from Nature Reviews Rheumatology brings together articles discussing the latest insights into the pathogenesis and management of OA.


  • The bispecific T cell engager (BiTE) blinatumomab showed promising clinical efficacy in a pilot study of six patients with multidrug-resistant rheumatoid arthritis.

    • Jessica McHugh
    Research Highlight
  • A wearable smart device that uses reconfigurable electronics and conductive polymer-based microneedles was able to monitor inflammation and provide transdermal drug delivery and electrical stimulation in a rat model of arthritis.

    • Maria Papatriantafyllou
    Research Highlight
  • Researchers have introduced the term ‘MDA5-autoimmunity and interstitial pneumonitis contemporaneous with the COVID-19 pandemic’ (MIP-C) to describe cases of MDA5 autoimmunity that surged during the COVID-19 pandemic.

    • Jessica McHugh
    Research Highlight
  • As the pace of genetic discovery has accelerated, so too has the need for clinicians and researchers to acknowledge and understand the impact of language in scientific publications. The use of inaccurate language contributes to systemic bias and eugenic ideologies that remain pervasive in biomedical science, including in rheumatology.

    • Paula S. Ramos
    • S. Sam Lim
25 years of biologic therapy

25 years of biologic therapy

Biologic therapies with various modes of action have been introduced into the field of rheumatology over the past 25 years, and have revolutionized the treatment and outcomes in many rheumatic diseases. This collection from Nature Reviews Rheumatology brings together articles on biologic therapy in rheumatology, including the latest Reviews and Opinion pieces, as well as popular content from our archives.