The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes.

The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes.

The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes.

The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes.

The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes.

The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes.

The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes.

Cover image supplied by James N. Sleigh, Institute of Neurology, University College London, London, UK. The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes. Photo copyright James N. Sleigh, supplied by Wellcome Collection (https://wellcomecollection.org/), licensed under CC-BY-NC 4.0 (https://creativecommons.org/licenses/by-nc/4.0/)/colours modified.

Cover image supplied by James N. Sleigh, Institute of Neurology, University College London, London, UK. The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes. Photo copyright James N. Sleigh, supplied by Wellcome Collection (https://wellcomecollection.org/), licensed under CC-BY-NC 4.0 (https://creativecommons.org/licenses/by-nc/4.0/)/colours modified.

Cover image supplied by James N. Sleigh, Institute of Neurology, University College London, London, UK. The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes. Photo copyright James N. Sleigh, supplied by Wellcome Collection (https://wellcomecollection.org/), licensed under CC-BY-NC 4.0 (https://creativecommons.org/licenses/by-nc/4.0/)/colours modified.

Cover image supplied by James N. Sleigh, Institute of Neurology, University College London, London, UK. The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes. Photo copyright James N. Sleigh, supplied by Wellcome Collection (https://wellcomecollection.org/), licensed under CC-BY-NC 4.0 (https://creativecommons.org/licenses/by-nc/4.0/)/colours modified.

Cover image supplied by James N. Sleigh, Institute of Neurology, University College London, London, UK. The image shows lower motor neurons, neuromuscular junctions and vascular plexus of mouse skeletal muscle. Lumbrical muscles of the hindfoot were dissected, and whole-mount immunofluorescent staining was performed before confocal imaging. The neuromuscular and vascular systems can be analysed in mouse models of neurological disorders, such as amyotrophic lateral sclerosis, Charcot–Marie–Tooth disease and spinal muscular atrophy, to enhance our understanding of the underlying neuropathological processes. Photo copyright James N. Sleigh, supplied by Wellcome Collection (https://wellcomecollection.org/), licensed under CC-BY-NC 4.0 (https://creativecommons.org/licenses/by-nc/4.0/)/colours modified.