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Neurosurgery

Complications of DBS surgery — insights from large databases

Nature Reviews Neurology volume 12, pages 617–618 (2016)Cite this article

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Analysis of data from a large number of deep brain stimulation (DBS) recipients in North America has revealed a higher rate of revisions and removals of DBS leads than was previously reported. Hardware malfunction, lead infection and malpositioning were the most frequent reasons for revision or removal.

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Figure 1: Complications of deep brain stimulation surgery.

References

  1. Okun, M. S. Deep-brain stimulation — entering the era of human neural-network modulation. N. Engl. J. Med. 371, 1369–1373 (2014).

    Article  Google Scholar 

  2. Kalia, S. K., Sankar, T. & Lozano, A. M. Deep brain stimulation for Parkinson's disease and other movement disorders. Curr. Opin. Neurol. 26, 374–380 (2013).

    Article  Google Scholar 

  3. Moro, E., Poon, Y. Y., Lozano, A. M., Saint-Cyr, J. A. & Lang, A. E. Subthalamic nucleus stimulation: improvements in outcome with reprogramming. Arch. Neurol. 63, 1266–1272 (2006).

    PubMed  Google Scholar 

  4. Benabid, A. L., Deuschl, G., Lang, A. E., Lyon, K. E. & Rezai, A. R. Deep brain stimulation for Parkinson's disease. Mov. Disord. 21, S168–S170 (2006).

    Article  Google Scholar 

  5. Bronte-Stewart, H. et al. Inclusion and exclusion criteria for DBS in dystonia. Mov. Disord. 26, S5–S16 (2011).

    Article  Google Scholar 

  6. Rolston, J. D., Englot, D. J., Starr, P. A. & Larson, P. S. An unexpectedly high rate of revisions and removals in deep brain stimulation surgery: analysis of multiple databases. Parkinsonism Relat. Disord. http://dx.doi.org/10.1016/parkreldis.2016.09.014 (2016).

  7. Okun, M. S. et al. Management of referred deep brain stimulation failures: a retrospective analysis from 2 movement disorders centers. Arch. Neurol. 62, 1250–1255 (2005).

    Article  Google Scholar 

  8. Falowski, S. M., Ooi, Y. C. & Bakay, R. A. Long-term evaluation of changes in operative techniques and hardware-related complications with deep brain stimulation. Neuromodulation 18, 670–677 (2015).

    Article  Google Scholar 

  9. Patel, D. M. et al. Adverse events associated with deep brain stimulation for movement disorders: analysis of 510 consecutive cases. Neurosurgery 11, 190–199 (2015).

    PubMed  Google Scholar 

  10. Reuter, S., Deuschl, G., Falk, D., Mehdorn, M. & Witt, K. Uncoupling of dopaminergic and subthalamic stimulation: life-threatening DBS withdrawal syndrome. Mov. Disord. 30, 1407–1413 (2015).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Elena Moro is at the Division of Neurology, Centre Hospitalier Universitaire de Grenoble, 38043 Grenoble, CS 10217, France.,

    Elena Moro

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  1. Elena Moro
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Correspondence to Elena Moro.

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Competing interests

The author has received personal compensation for serving on the Medtronic scientific advisory board. She has also received speaker honoraria from Medtronic.

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Moro, E. Complications of DBS surgery — insights from large databases. Nat Rev Neurol 12, 617–618 (2016). https://doi.org/10.1038/nrneurol.2016.163

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