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Volume 17 Issue 1, January 2021

Volume 17 Issue 1

The Sustainable Development Goals, inspired by this month’s Focus issue

Image: Lara Crow. Cover design: Lara Crow.



Research Highlights



  • Perspective |

    SGLT2 inhibitors induce a number of metabolic adaptations in response to increased glucose and Na+ excretion. This Perspective article describes how these adaptations suggest that SGLT2 inhibition triggers a body water-conserving mechanism, and discusses how these metabolic adjustments may contribute to the favourable cardiovascular and renal outcomes of this class of therapeutics.

    • Adriana Marton
    • , Tatsuroh Kaneko
    •  & Jens Titze


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