Reviews on metabolism in PKD and the molecular classification of nephrotic syndrome, Perspectives on uric acid in CKD and approaches to understand sex differences in kidney disease, plus commentaries on Advancing American Kidney Health, treatment of renal anaemia, and the structure of NKCC1.

Reviews on haemolysis-induced kidney injury and the (pro)renin receptor, a Consensus Statement on the diagnosis and management of ADPKD in children and young people, plus commentaries on artificial intelligence to predict AKI, the MENTOR trial, disparities between trial cohorts and patients, and lipid lowering in CKD.

Reviews on hypoxia signalling, acute tubular injury subtypes, kidney organoids and the immunology of ageing, plus commentaries on increasing diversity in STEM, kidney metabolism and nephropathic autoantigens.

Reviews on the microbiome, extracellular DNA traps, and the effect of sodium on immune cells, a Consensus Statement on GH treatment in children with CKD, and commentaries on data sharing, SGLT2 inhibitors in PTDM and genomic collision in transplantation.

Reviews on antimicrobial resistance, phosphate transport and inflammasomes, plus commentaries on the SONAR, CREDENCE and DELIGHT trials.

Reviews on the ubiquitin–proteasome system, polycystin structure and function, adjuvant treatment of kidney cancer, a Consensus Statement on the diagnosis and management of X-linked hypophosphataemia, plus commentaries on cardiovascular disease in ESRD and gut microbial SCFAs and diabetes risk.

Reviews on epigenetics in diabetic kidney disease, glycosylation and obesity-induced hypertension, plus commentaries on the genetic basis of CKD, haemodialysis for undocumented immigrants and treatment of metastatic kidney cancer.

Reviews on immune system and microbiota interactions, pre-eclampsia, immune mechanisms of salt-sensitive hypertension and the uraemic syndrome, plus commentaries on albuminuria as a surrogate end point in clinical trials, an approach to vascularize kidney organoids and the PIVOTAL trial of iron in CKD.

Reviews on cilia signalling, the genetics of Wilms tumour and epigenetics in AKI, plus commentaries on the global burden of kidney disease, metabolism in AKI and DNA methylation in nephrogenesis.

Reviews on C3 glomerulopathy, macrophages in inflammation and fibrosis, and uraemic cardiomyopathy, a Perspective on estimating GFR, and commentaries on sodium transport in diabetes and peritoneal dialysis solutions.

Interdigitating foot processes of podocytes attached to glomerular capillaries, imaged by scanning electron microscopy.

Reviews on B cells in immune-mediated kidney disease and Klotho proteins in health and disease, a Consensus Statement on the evaluation of monoclonal gammopathy of renal significance, and commentaries on expression quantitative trait loci for genomic discovery, the timing of renal replacement therapy in critical care, and albuminuria as a cause of hypertension.