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In this Comment, Linzie Taylor and Karen Rommelfanger argue that white Western individualist bias is impeding progress in neuroscience and present a relational rubric of principles to mitigate this bias.
Neuronal activity in a key region of the mouse hypothalamus modulates adult hippocampal neurogenesis, promoting the formation of adult-born neurons that support cognition and affective function.
In rodents, absence seizures — a prominent manifestation of generalized epilepsy — drive activity-dependent myelination in the corpus callosum, increase interhemispheric synchrony and drive increases in seizure burden over time.
A population of spinal interneurons that express prokineticin receptor 2 is needed in mice for the rewarding, antistress and prosocial effects of pleasant touch.
During brain development, cortical circuits form in a stepwise manner through self-organization and activity-dependent adjustment. Cossart and Garel describe the stages that characterize this process and highlight the crucial contributions made by cortical neurons that adopt multiple cellular functions as their development progresses.
Macroautophagy involves the delivery of various macromolecules and organelles to lysosomes for degradation. In this Review, Christopher Griffey and Ai Yamamoto provide an overview of this intracellular process and consider its modulation under physiological conditions and in brain disorders.
The orbitofrontal cortex (OFC) has long been thought to track value, but new data implicate the OFC in the representation of cognitive maps of associative relationships. Here, Knudsen and Wallis review these hypotheses and examine how they might be reconciled.
Various theories have been developed for the biological and physical basis of consciousness. In this Review, Anil Seth and Tim Bayne discuss four prominent theoretical approaches to consciousness, namely higher-order theories, global workspace theories, re-entry and predictive processing theories and integrated information theory.
