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Volume 21 Issue 1, January 2020

Volume 21 Issue 1

‘A mouse’s-eye view’ inspired by the Review on p5.

Cover design: Jennie Vallis.

Research Highlights

Reviews

  • Review Article |

    Although the retinas of most vertebrates share the same basic blueprint, there is substantial variability in their detailed structure and function. Baden and colleagues describe the extent of this diversity and explore the factors that contribute to species-specific adaptations in retinal organization.

    • Tom Baden
    • Thomas Euler
    • Philipp Berens
  • Review Article |

    In Alzheimer disease, the accumulation of amyloid-β (Aβ) is thought to drive both tau pathology and neurodegeneration. In this Review, van der Kant et al. discuss the evidence for Aβ-independent drivers of tau pathology in Alzheimer disease and the implications for therapeutic development.

    • Rik van der Kant
    • Lawrence S. B. Goldstein
    • Rik Ossenkoppele
  • Review Article |

    The impact of RNA modifications, such as RNA methylation, on gene expression and cellular function has been the subject of recent intense investigations. Here Dominissini and colleagues provide an overview of the mechanisms of such epitranscriptomic regulation and their functional consequences in the nervous system.

    • Ido Livneh
    • Sharon Moshitch-Moshkovitz
    • Dan Dominissini

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