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Targeted ultrasound stimulation can specifically modulate the functional connectivity profiles of targeted structures — including deep structures — in the macaque brain, with effects lasting for up to 2 hours following stimulation.
The sexually dimorphic responses of male and female mice to their young are regulated by the activity of a specific population of neurons in the medial amygdala.
It is now clear that most classical ‘cell types’ are composed of collections of cells with heterogeneous features. Cembrowski and Spruston describe the heterogeneity of hippocampal pyramidal cells and argue that these cells can act as a model of within-cell-type heterogeneity in the brain.
Recent years have seen a growing interest in the neurobiological basis of paternal caregiving. Feldman and colleagues review studies that have shed light on the circuits that underlie paternal care in mammals and the consequences of this care for fathers and their offspring.
How does the brain generate positive or negative hedonic or motivational reactions (such as liking or disgust) to particular stimuli or events? In this Opinion article, Berridge evaluates two proposed mechanisms for the generation of affective valance in the brain.
Environmental enrichment is a classical experimental paradigm for the study of the interaction between genes and the environment. In this Opinion, Kempermann discusses how this paradigm can be further developed in order to capture the essence of interindividual differences in brain function.