A population of spinal excitatory interneurons can be targeted for the maintenance of respiratory function after spinal cord injury in mice.
Volume 19 Issue 12, December 2018
Nonsense-mediated RNA decay — a highly selective and conserved RNA turnover pathway — is shown to have roles in both brain development and function. In this Review, Jaffrey and Wilkinson discuss how this pathway affects the nervous system.
Astrocytes display widespread functional diversity that translates into distinct regulation of synaptic circuits. In this Review, Dallérac and colleagues discuss the determinants of these divergent regulations throughout life focusing on astroglial intrinsic heterogeneity, developmental changes and activity-dependent processes.
Sharp wave–ripples (SWRs) are specific neural activity patterns in the hippocampus that are thought to support memory. In this Review, Hannah Joo and Loren Frank explore where and when SWRs are generated and propose a revised view of the role of these activity patterns in memory functions.
Animals may adopt an active-sampling strategy to assess their environment. In this Review, Jacqueline Gottlieb and Pierre-Yves Oudeyer explore the emerging neuroscientific literature examining active sampling and how it relates to attention and curiosity.