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Volume 12 Issue 4, April 2011

From The Editors

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Research Highlight

  • A link between PACAP–PAC1 and post-traumatic stress disorder in women has been identified.

    • Katie Kingwell
    Research Highlight
  • Context-induced relapse to heroin seeking is triggered by the activation of a subset of neurons in the ventral medial prefrontal cortex.

    • Leonie Welberg
    Research Highlight
  • A neural correlate between aggressive behaviour and mating has been found. This involves a set of neurons in the ventromedial hypothalamus that are active during fighting and suppressed during mating.

    • Sian Lewis
    Research Highlight
  • Hot- and cold-sensing neurons form a thermotopic map in the fly brain

    • Monica Hoyos Flight
    Research Highlight
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In Brief

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Research Highlight

  • The timing of cell birth influences neuronal projections from the olfactory bulb to the olfactory cortex.

    • Monica Hoyos Flight
    Research Highlight
  • Zinc finger protein 521 (ZFP521) drives neural induction in embryonic stem cells.

    • Katherine Whalley
    Research Highlight
  • Early tagging of cortical neurons after memory encoding is required for subsequent memory consolidation.

    • Katie Kingwell
    Research Highlight
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In Brief

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Review Article

  • The growth cones of developing axons are guided towards their targets by gradients of cues. Kamiguchi and colleagues propose a mechanism for this process whereby cues trigger an alteration in the balance of endocytosis and exocytosis on one side of the growth cone, biasing the direction of turning.

    • Takuro Tojima
    • Jacob H. Hines
    • Hiroyuki Kamiguchi
    Review Article
  • Vesicular glutamate transporters are expressed not only in glutamate neurons but also in monoamine, acetylcholine and, intriguingly, GABA neurons. Trudeau and colleagues discuss the role of these transporters in glutamate co-release and vesicular synergy — a process leading to enhanced packaging of the 'primary' transmitter.

    • Salah El Mestikawy
    • Åsa Wallén-Mackenzie
    • Louis-Eric Trudeau
    Review Article
  • Various proposals have defined the dorsal visual stream as a 'Where' or 'How' pathway. Synthesizing data from anatomical and functional studies, Mishkin and colleagues propose that in the posterior parietal cortex, three different pathways emerge from the dorsal stream, each supporting a different aspect of spatial processing.

    • Dwight J. Kravitz
    • Kadharbatcha S. Saleem
    • Mortimer Mishkin
    Review Article
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Opinion

  • Although inter-individual differences in performance are often considered to be 'noise', recent data show that they are linked to structural differences. Kanai and Rees argue that studying these links can help in understanding how structural variation influences the functional capacity of brain regions.

    • Ryota Kanai
    • Geraint Rees
    Opinion
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