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  • A subset of female mice that show anxiety-related traits seek out a starvation-like state when exposed to repeated stress

    • Katherine Whalley
    Research Highlight
  • The main direction of motor skill-specific information between rat primary motor cortex and dorsolateral striatum is shown to switch from cortex-predominant before learning to striatum-predominant after learning.

    • Sian Lewis
    Research Highlight
  • A large network of brain regions is involved in salient distractor processing.

    • Isobel Leake
    Research Highlight
  • A new study captures nearly the full repertoire of primate natural behaviour and reveals that highly distributed cortical activity maintains multifaceted dynamic social relationships.

    • Jake Rogers
    Research Highlight
  • The synaptic protein SynGAP exerts its effects on synaptic plasticity via a structural role rather than its GTPase-activating protein activity.

    • Darran Yates
    Research Highlight
  • One of the long-term sequelae associated with SARS-CoV-2 infection is ‘brain fog’, which is shown in this study to be linked to systemic inflammation and leakiness of the blood–brain barrier.

    • Sian Lewis
    Research Highlight
  • Neurons in the mouse subiculum encode concave and convex geometrical environmental features.

    • Katherine Whalley
    Research Highlight
  • Innate fear-like responses are thought to involve the amygdala, but here a tetra-synaptic pathway is identified that mediates odour-evoked innate fear in mice.

    • Sian Lewis
    Research Highlight
  • Populations of neurons in the mouse hippocampus use distinct representational strategies to encode familiarity and episodic social memory.

    • Katherine Whalley
    Research Highlight
  • Increased levels of matrix metalloproteinase 8, expressed by circulating myeloid cells, may have a role in stress-induced changes in social behaviour in mice.

    • Darran Yates
    Research Highlight
  • Blood pressure pulsations modulate the activity of neurons in the rodent olfactory bulb via the mechanosensitive ion channel PIEZO2

    • Katherine Whalley
    Research Highlight
  • In this Journal Club, Valeria Della-Maggiore highlights a 2017 paper that provided key evidence for a role for the hippocampus in motor skill learning

    • Valeria Della-Maggiore
    Journal Club
  • In mice, a subset of neurons in the dorsomedial hypothalamus control sympathetic nervous system signalling to adipose tissue and are dysregulated with age; activating these neurons prolongs lifespan and slows the decline in physical activity associated with ageing.

    • Joseph Willson
    Research Highlight
  • A study analyses the nanotopography of presynaptic calcium channels and release sensors and the degree of their coupling during maturation of an inhibitory synapse.

    • Lisa Heinke
    Research Highlight
  • Around 10% of individuals with frontotemporal lobar dementia have amyloid filament inclusions that lack tau and TDP-43 and were thought to contain the protein FUS, but are found instead to contain the FUS homologue TAF15.

    • Sian Lewis
    Research Highlight