Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
In mice, projections from the prelimbic cortex to the nucleus accumbens encode a combination of social and spatial information and may promote 'social investigation' behaviour by enabling social–spatial learning.
Ca2+-independent but voltage-dependent secretion is mediated by the voltage-gated calcium channel subunit CaV2.2, is enabled by SNARE machinery and results in release of ATP or neuropeptide Y.
A study reports that low-amplitude intracortical microstimulation in the premotor cortex can be used to induce movements in monkeys by learned association.
A reduction in the level of T cell intracellular antigen 1, an RNA-binding protein, was protective for tau-induced neuronal death in a mouse model of tauopathy.
Among isogenicCaenorhabditis elegansnematodes, some individuals show biases in aspects of foraging behaviour that persist over development, and this individual-level variation in behaviour is subject to neuromodulatory regulation.
The brain comprises complex structural and functional networks, but much remains to be determined regarding how these networks support the communication processes that underlie neuronal computation. In this Review, Avena-Koenigsberger, Misic and Sporns discuss the network basis of communication dynamics in the brain.
The brain uses predictable temporal structure to anticipate and select relevant events in time. Nobre and van Ede introduce different types of this 'temporal expectation' and its neural underpinnings, and describe how temporal expectation interacts with other forms of expectation in guiding adaptive behaviour.
At hippocampal mossy fibre synapses, depolarization-induced facilitation of vesicle release occurs via a cAMP-dependent increase in coupling between Ca2+ channels and vesicle release machinery.
A method that integrates whole-brain neural activity measurements with cellular-level molecular phenotyping is used to investigate the neuronal populations that modulate a global brain state.
