Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Cell-surface receptors of the Dscam family are required for neuronal wiring inDrosophila. Schmucker discusses the homophilic-binding specificity and diversity of these receptors, their potential role in different aspects of neuronal wiring and key questions that remain unanswered.
Membrane phosphoinositides are important for generating key intracellular second messengers and are also able to directly regulate the activity of membrane proteins. Gamper and Shapiro discuss the regulatory actions of phosphoinositides on a range of neuronal ion channels and transporters.