In this Journal club, Teruhiro Okuyama discusses the 2005 article that demonstrated the existence of ‘concept cells’ in the medial temporal lobe that show selective responses to specific individuals and play a key role in social memory.

Philip Tovote describes the 1980 paper in which Michael Fanselow systematically investigated freezing as a defensive response in rodents

An array of genetically encoded tools are now available to label and manipulate synapses in different experimental species. Kaang and colleagues provide an overview of these techniques, highlighting their advantages, disadvantages and utility for investigating synaptic function.

During their maturation, mammalian neurons lose the capacity to regrow their axons after an injury. Here, Hilton et al. explore the neuron maturation processes that limit axon regeneration, including changes in gene expression, cytoskeletal dynamics, and intracellular signalling and trafficking.

Blocking voltage-gated calcium channels reduces capillary narrowing by pericytes and improves cerebral blood flow in a mouse model of Alzheimer disease.

An anterior cingulate cortex to lateral septum circuit underlies the drive of spiny mice to affiliate with larger groups in preference to smaller ones.

Mice that witness a cage mate’s distress become resilient to future adverse events as a result of altered serotonin release in the lateral habenula.

In this Journal club, Teruhiro Okuyama discusses the 2005 article that demonstrated the existence of ‘concept cells’ in the medial temporal lobe that show selective responses to specific individuals and play a key role in social memory.

Diet-induced obesity in mice is accompanied by hypothalamic inflammation, which is shown here to result in thickened perineuronal nets in arcuate nucleus neurons, insulin resistance and metabolic disease.

Philip Tovote describes the 1980 paper in which Michael Fanselow systematically investigated freezing as a defensive response in rodents