Navigating for reward

  • Marielena Sosa
  • Lisa M. Giocomo
Review Article

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    • Many studies implicate a prefrontal–basal ganglia circuit in the control of action-stopping. Here, Ricci Hannah and Adam Aron provide an update of studies of this circuit, discuss its clinical relevance, and consider whether its action-stopping function applies in real-world scenarios, beyond the laboratory.

      • Ricci Hannah
      • Adam R. Aron
      Review Article
    • Mammalian skin contains an array of specialized structures that transform mechanical forces into electrical signals. Handler and Ginty provide a comprehensive overview of the features of the skin’s mechanosensory end organs and the neurons with which they associate and consider how their diverse properties contribute to the sense of touch.

      • Annie Handler
      • David D. Ginty
      Review Article
    • The brain is particularly susceptible to injury after ischaemia; however, emerging evidence suggests that, under certain conditions, it may show more resilience. Daniele et al. review the effects of ischaemia on the brain and efforts to study and protect the post-ischaemic brain.

      • Stefano G. Daniele
      • Georg Trummer
      • Nenad Sestan
      Review Article
    • The capacity to navigate to a previously encountered or predicted reward, such as food or safety, is crucial for survival. Here, Sosa and Giocomo examine the neural mechanisms that encode reward location and propose key roles for the hippocampus and the entorhinal cortex in storing and retrieving reward-related information in the brain.

      • Marielena Sosa
      • Lisa M. Giocomo
      Review Article
    • Regions of the default mode network (DMN) are distributed across the brain and show patterns of activity that have linked them to various different functional domains. In this Perspective, Smallwood and colleagues consider how an examination of the topographic characteristics of the DMN can shed light on its contribution to cognition.

      • Jonathan Smallwood
      • Boris C. Bernhardt
      • Daniel S. Margulies
      Perspective
20th Anniversary

20th Anniversary

The October 2020 issue of Nature Reviews Neuroscience marks 20 years since the journal was launched.
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