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On this page: Article types and instructions | Writing tips | How to submit | Publishing model

Article types and instructions

Nature Reviews Methods Primers primarily publishes Primer articles. Please also ensure that you have read and understood our editorial policies.

Large Language Models (LLMs), such as ChatGPT, do not currently satisfy our authorship criteria. Notably an attribution of authorship carries with it accountability for the work, which cannot be effectively applied to LLMs. Use of an LLM should be properly documented in the Methods section (and if a Methods section is not available, in a suitable alternative part) of the manuscript.

Writing tips

Articles written for the Nature Reviews journals are targeted towards readers from an advanced undergraduate level upwards in addition to being of interest to specialists, and should be accessible to readers working in related disciplines. Some basic guidelines to improve clarity and readability of your article are:

  • Authors should provide sufficient background information to ensure the discussion can be understood by non-expert readers.
  • Authors should discuss the implication of the work under discussion, rather than simply describe a study's findings.
  • Although the discussion within an article should be balanced, authors should not list or describe every paper within the field; we expect authors to select, discuss and interpret the papers they feel are most important.

Overuse of abbreviations, acronyms or jargon-laden language can hamper readability. Authors should, therefore, use plain language to explain concepts and restrict the use of abbreviations while adhering to the agreed word limit. 

Our typographic and house styles are used to ensure clarity and consistency within and between articles and journals. Some useful tips  to help you prepare an article for publication in a Nature Reviews journal are:

  • Use standard gene and protein nomenclature — for example, human genes (uppercase and italic), human proteins (uppercase), mouse genes (first letter only uppercase and italic) and mouse proteins (uppercase). If it’s not clear which species is being referred to, we default to human nomenclature; thus, please specify when referring to mouse genes. To avoid delays at the proof stage, please consult the appropriate nomenclature databases for standard gene names and symbols. Useful resources are and
  • Use SI units in all instances.
  • For drugs, use International Nonproprietary Names as a default whenever possible.

How to submit

Synopses and manuscripts must be submitted electronically through our online submission system, using the link and instructions provided by the editor. Proposals should also be submitted through the journal’s online submission system in the form of a synopsis (consisting of a 200‑word abstract, a brief description of the main article sections, a list of key references and the list of authors and their affiliations). Please note that we consider proposals only for Review-type and Comment-type articles and that we do not publish original research, case studies, meta-analyses or systematic reviews. 

Publishing model

Articles published in Nature Reviews can only be published using the subscription publication route; we do not offer an immediate gold open access (OA) publication option.  

Nature Reviews only publishes non-primary articles  (such as Reviews, News & Views and Comment articles). In contrast to primary articles (that is, research articles), non-primary articles do not include original (previously unpublished) research findings and may only contain minimal re-analyses of published data.

Six months after the date of online publication, authors of articles published in the Nature Reviews journals can self-archive the accepted manuscript on their own personal website and/or in their funder or institutional repositories. By agreeing to write for a Nature Reviews journal, authors agree to accept our standard licensing terms including our self-archiving policies. Those standard licensing terms supersede any other terms that the author or any third party may assert apply to any version of the manuscript.