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Volume 20 Issue 3, March 2022

In remembrance of Howard C. Berg, Review on p161

Cover design: Philip Patenall

Volume 20 Issue 3

Comment

  • The International Committee on Systematics of Prokaryotes (ICSP) has recently altered long-standing phylum names and given no guidance for taxonomy of uncultured or imperfectly cultured archaea and bacteria, disrupting progress towards a universal system of microbial taxonomy. Inclusion of new members into ICSP may help it to keep up to date.

    • Karen G. Lloyd
    • Guillaume Tahon
    Comment

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Research Highlights

  • Recent studies provide new insights into the regulation of lysogeny and prophage induction.

    • Andrea Du Toit
    Research Highlight
  • This study shows how a satellite RNA manipulates both its host plant and aphid vector to ensure efficient transmission.

    • Ursula Hofer
    In Brief
  • A mouse study shows a link between the microbiome, smoking cessation and weight gain, resembling preliminary results in humans.

    • Ursula Hofer
    In Brief
  • This study reports the discovery of new broad-spectrum metallo-β-lactamase inhibitors with a unique binding mode.

    • Ursula Hofer
    In Brief
  • A recent study found that constituents of the gut virome are negatively associated with seroconversion following rotavirus vaccination, possibly explaining the diminished effectiveness of rotavirus vaccines in low- and middle-income countries.

    • Ashley York
    Research Highlight
  • This study compares an equine influenza virus shortly after its jump into horses with a contemporary strain, showing how it adapted to the new host.

    • Ursula Hofer
    In Brief
  • This study determines how the climate influences the transmission of Wolbachia in flies.

    • Ursula Hofer
    In Brief
  • This study describes how a marine cyanobacterium carries out nitrogen and carbon fixation at the same time.

    • Ursula Hofer
    In Brief
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News & Analysis

  • This month’s Genome Watch article highlights integrative approaches for discovering metabolites and microorganisms that improve cognitive performance.

    • Ying Wang
    • Trent R. Northen
    Genome Watch
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Reviews

  • In this Review, Perry, Meirelles and Newman review the growing body of evidence that microbial secondary metabolites can modulate susceptibility to commonly used antibiotics, focusing on the mechanisms and why this phenomenon occurs, and they discuss the implications for the diagnosis of antibiotic resistance and therapeutic strategies.

    • Elena K. Perry
    • Lucas A. Meirelles
    • Dianne K. Newman
    Review Article
  • Mass spectrometry-based metabolomics is one of the key technologies to detect and identify the small molecules produced by the human microbiota and to understand the functional role of these microbial metabolites. In this Review, Dorrestein and colleagues review common forms of untargeted mass spectrometry and the types of data that can be obtained in the context of microbiome analysis.

    • Anelize Bauermeister
    • Helena Mannochio-Russo
    • Pieter C. Dorrestein

    Series:

    Review Article
  • In this Review, Wadhwa and Berg explore the most common bacterial motility mechanisms and summarize the current understanding of the molecular machines that enable bacteria to swim in aqueous media and move on solid surfaces.

    • Navish Wadhwa
    • Howard C. Berg
    Review Article
  • Lipid biomarkers provide insights into the nature and history of the Earth’s microbial life. In this Review, Summons et al. discuss how advances in molecular biology have helped elucidate lipid biomarker origins and afforded robust interpretations of fossil lipids, and explore key examples of how genomics-enabled advances in lipid biomarker science are illuminating the history of microbial life on the Earth.

    • Roger E. Summons
    • Paula V. Welander
    • David A. Gold
    Review Article
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