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This study reports whole genomes for all known Laverania species, providing insights into the emergence of Plasmodium falciparum as a major human pathogen.
In this study, Hernandez-Doria and Sperandio show that enterohaemorrhagic Escherichia coli harbour dormant phages that express a transcription factor that regulates bacterial virulence factors.
This month’s Genome Watch highlights discoveries of high variability in the genes underlying cytoplasmic incompatibility among Wolbachia strains that help identify the best strains to use for the control of vector-borne diseases such as Zika virus and malaria.
Implant infections are often resistant to treatment and immune responses owing to the formation of biofilms. In this Review, Arciola, Campoccia and Montanaro summarize the strategies that pathogens such as staphylococci use to infect implants and novel treatment approaches.
Complex microbial communities shape the dynamics of various environments. In this Review, Knight and colleagues discuss the best practices for performing a microbiome study, including experimental design, choice of molecular analysis technology, methods for data analysis and the integration of multiple omics data sets.
Ubiquitin-like protein ISG15 is an interferon-induced protein that has been implicated as a central player in the host antiviral response. In this Review, Perng and Lenschow provide new insights into how ISG15 restricts and shapes the host response to viral infection and the viral immune-evasion strategies that counteract ISG15.
In this Review, Jennings and colleagues discuss interactions involving host and bacterial glycans that have a role in bacterial pathogenesis. They also highlight recent technological advances that have illuminated the glycoscience of microbial pathogenesis.
