Research Highlights

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  • This study shows that intercellular long extensions promote the evasion of antibody neutralization and the efficient intercellular transmission of chikungunya virus in vitro and in vivo.

    • Andrea Du Toit
    Research Highlight
  • This study shows that a gut peptide is active against virulent forms of Candida albicans, thus contributing to the maintenance of fungal commensalism.

    • Andrea Du Toit
    Research Highlight
  • In this study, Huang et al. discover Delftia tsuruhatensis TC1, a mosquito symbiotic bacterium that inhibits parasite development via the secretion of a small molecule.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Sharafutdinov et al. report a single nucleotide polymorphism in the gene encoding the HtrA protease of Helicobacter pylori that is associated with gastric cancer.

    • Agustina Taglialegna
    Research Highlight
  • This study shows that Haloferax volcanii uses its type IV pili for cell attachment to a surface and mechanical cohesion between cells under flow conditions, thus promoting biofilm development.

    • Andrea Du Toit
    Research Highlight
  • In this study, Gül et al. show that usage of different carbon sources by Enterobacteriaceae strains determines their expansion and co-existence in the mouse gut and favours plasmid transfer.

    • Agustina Taglialegna
    Research Highlight
  • The study reveals how a satellite phage-encoded protein directs the assembly of coat proteins into small capsids.

    • Andrea Du Toit
    Research Highlight
  • In this study, Tsuji et al. report the glycolipid 7DW8-5 that exploits the host innate immune system to control SARS-CoV-2, respiratory syncytial virus and influenza virus infections.

    • Agustina Taglialegna
    Research Highlight
  • The authors developed a refillable, long-acting subcutaneous nanofluidic antiretroviral delivery implant that conferred protection against infection with simian–human immunodeficiency virus in rhesus macaques.

    • Andrea Du Toit
    Research Highlight
  • In this study, Douglas et al. examine the role of the staphylococcal TcaA protein in human serum susceptibility during bacteraemia.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Irazoki et al. show that Vibrio cholerae releases d-amino acids into the environment, which are sensed by a bacterial chemoreceptor to prompt a repellent chemotactic response.

    • Agustina Taglialegna
    Research Highlight
  • This study provides insights into the mechanism whereby Citrobacter rodentium transitions from the intestinal lumen to its mucosal niche.

    • Andrea Du Toit
    Research Highlight
  • This study suggests that pre-existing DENV immunity has a negative effect on the pathogenesis of secondary ZIKV infection during pregnancy in marmosets.

    • Andrea Du Toit
    Research Highlight
  • This study reveals the conformational changes of the utilisome that facilitate glycan processing and import.

    • Andrea Du Toit
    Research Highlight
  • This study reports that an engineered bee symbiont provides protection against Nosema ceranae infection.

    • Andrea Du Toit
    Research Highlight
  • In this study, Fidelle et al. show that recolonization of the gut by Enterocloster spp. after antibiotic treatment compromises the anticancer effect of immune checkpoint inhibitor therapy.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Catchpole et al. identify the first self-transmissible conjugative plasmid in the euryarchaeon Thermococcus sp. 33-3 and use it to genetically modify diverse hyperthermophilic archaea.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Vidakovic et al. show that during infection Vibrio cholerae forms biofilms on the surface of human immune cells to kill them and then disperses.

    • Agustina Taglialegna
    Research Highlight