In Brief

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  • A recent study showed that the gut microbiota regulates innate immune signalling and protective immunity against cancer in mice.

    • Ashley York
    In Brief
  • This study identified a functional restriction modification system in the mitochondrial genome of a marine protist that originated in bacteria.

    • Ashley York
    In Brief
  • A recent study found that high partial pressures of CO2 such as those found in hydrothermal environments drive the tricarboxylic acid cycle backwards towards autotrophy in a thermophilic bacterium.

    • Ashley York
    In Brief
  • This study finds that a bacterium commonly found in cold environmental habitats evolved from a mammalian pathobiont.

    • Ursula Hofer
    In Brief
  • This study found that bacteria induce skin regeneration via inflammatory cytokine IL-1β signalling.

    • Ashley York
    In Brief
  • A recent study found that Akkermansia muciniphila secretes a glucagon-like peptide-1-inducing protein that improves glucose homeostasis and ameliorates metabolic disease in mice.

    • Ashley York
    In Brief
  • A recent study found that an archaeal virus interferes with the cell cycle of its host, leading to asymmetric cell division and cell gigantism, transforming hosts into giant virion-producing factories.

    • Ashley York
    In Brief
  • This study reveals that mites reduce emission of nitrous oxide (N2O) from soil by feeding on N2O-producing fungi, so modulating mite abundance might represent a way to mitigate anthropogenic N2O emissions in agriculture.

    • Grant Otto
    In Brief
  • This study examines microbial evolution, in the form of biofilm-producing ability, in the context of microbiome ecology and shows that both have an impact on host fitness.

    • Grant Otto
    In Brief
  • This study demonstrates that an N6-methyladenosine (m6A) modification in the internal ribosome entry site of the hepatitis C virus RNA genome affects translation initiation through the action of the m6A reader protein YTHDC2 and its interaction with the La antigen.

    • Grant Otto
    In Brief
  • This study reports the development of a skin commensal bacterium as a bacteriotherapy for atopic dermatitis and finds that it is safe and potentially effective in a phase I clinical trial.

    • Grant Otto
    In Brief
  • This study reports that there is a seasonal transition in soil microbiome composition and functioning in alpine regions and that climate change may alter the timing of this transition and affect biogeochemical cycling and nutrient availability.

    • Grant Otto
    In Brief
  • This study reports the discovery of an anaerobic ciliate with reduced mitochondria that secondarily acquired a bacterial endosymbiont enabling the host to generate energy by denitrification.

    • Grant Otto
    In Brief
  • This study provides evidence that membrane lipids are important in regulating the dynamics of the bacterial mechanosensitive channel MscS in response to changes in membrane tension.

    • Grant Otto
    In Brief
  • This study provides ultrastructural evidence that the HIV-1 capsid can enter the nucleus of an infected T cell line through the nuclear pore complex and fragments in the nucleoplasm to release the viral genome.

    • Grant Otto
    In Brief
  • This study reports that childhood antibiotic exposure alters the gut microbiota, resulting in reduced growth in boys and increased body mass index in boys and girls, from exposure in infancy and early childhood, respectively.

    • Grant Otto
    In Brief
  • This study shows that one mechanism of immune evasion used by Staphylococcus aureus involves a virulence factor, SpA, which can block complement activation by inhibiting IgG oligomerization.

    • Grant Otto
    In Brief
  • This study reveals that Toxoplasma gondii maintains a replicative niche in neutrophils by extending their longevity through inhibition of apoptosis. This effect occurs by upregulation of PCNA expression, resulting in inhibition of caspase cleavage and activation.

    • Grant Otto
    In Brief