Genome Watch

This month’s Genome Watch highlights the recent use of machine learning to uncover functional ‘dark matter’ in the microbial protein universe.

This Genome Watch highlights how a tailor-made search through bacterial genomes revealed the widespread presence of a new class of bacterial signalling peptides that lack conventional characteristics.

This Genome Watch highlights different tools and strategies used to enhance the quality of metagenome-assembled genomes (MAGs) generated in microbiome studies.

This month’s Genome Watch highlights the use of high-depth genome-centric approaches to further our understanding of the human gut microbiome within the context of industrialized and non-industrialized lifestyles.

This Genome Watch highlights how the integration of genomic surveillance with epidemiological or clinical data can help understand pathogen transmission and improve public health interventions for infectious disease control.

This Genome Watch highlights new computational approaches aimed at circumventing contamination in low-biomass microbiome studies.

This Genome Watch highlights the recent developments of prokaryotic nomenclature leading to the coexistence of two parallel prokaryotic nomenclatural codes.

This Genome Watch highlights how combining next-generation sequencing and imaging technologies sheds light on the diverse and intricate symbiotic relationships of uncultivated archaea and bacteria.

This Genome Watch highlights recent metagenomics studies in fish that reveal unique microbiomes with low functional diversity, which could help to improve our understanding of host–microorganism dynamics in non-mammalian species.

This Genome Watch explores how large-scale microbiome studies are facilitating discoveries in bacteriophage biology and functional capabilities that are prime for translation towards advances in biotechnology and biotherapeutics.

This month’s Genome Watch explores how synonymous mutations may have wider implications for protein function than previously acknowledged.

This Genome Watch explores how metagenomics aids in profiling plant-derived microorganisms and molecules that could have an impact on the composition and function of the human gut microbiome.

This Genome Watch article explores how portable sequencing technology is re-shaping the field of genomic epidemiology.

This month’s Genome Watch highlights how genome sequencing can be used to understand the strain-level diversity, evolution and spatial structure of the human microbiome, and to inform therapeutic strategies.

This Genome Watch article highlights how single-cell sequencing has transformed the approaches to understand schistosome developmental biology.

This Genome Watch explores how metagenomics and bioinformatics can aid to uncover the prevalence and biosynthetic capabilities of underexplored microorganisms in various ecosystems.

This Genome Watch highlights how population genomic strategies can aid in the development of an effective syphilis vaccine.

This Genome Watch highlights how studying endosymbiotic gene transfer in more recently established endosymbioses sheds light on how the algal plastid evolved more than a billion years ago.

This Genome Watch highlights recently reported methods that enable genome editing of microorganisms within phylogenetically diverse communities.

This Genome Watch highlights how metagenomics can fill the knowledge gap of the wild avian gut microbiome and enable the early detection of antibiotic-resistant bacteria with implications for public health policy and conservation management.