Research Highlights

In this study, Simonis et al. show that chronic infection with Pseudomonas aeruginosa leads to development of neutralizing antibodies that could be exploited to fight against this pathogen.

In this study, Wang et al. show that bacterium-derived intestinal ammonia modulates glutamine production in the mouse brain and reduces stress-induced depressive-like behaviour.

This study provides evidence for a role of Anopheles stephensi in driving urban malaria outbreaks.

This study reports the identification of an archaeal virus Acr protein that blocks the dissociation of the target RNA from the type III-B CRISPR–Cas effector complex, which prevents the recycling of the complex.

This study reports that intracellular cord formation by Mycobacterium tuberculosis is an important feature of early pathogenesis.

In this study, Yan et al. developed a broad-spectrum protein-free vaccine that protects against infection with bacterial and fungal nosocomial pathogens.

This study reports the identification of the novel Candida auris-specific adhesin Scf1, which, together with the adhesin Iff4109, is a key mediator of surface association, infection and long-term colonization.

This study found that the bacterial second messenger cyclic diguanylate (c-di-GMP) has a key role in establishing host–bacteria symbiosis.

A recent study found that carbohydrate metabolism by gut microbiota contributes to insulin resistance.

This study shows how the bacterium Akkermansia muciniphila exacerbates food allergy in fibre-deprived mice.

In this study, Prasad et al. show that Alcanivorax borkumensis optimizes oil consumption via formation of tubular biofilms.

This study shows that intercellular long extensions promote the evasion of antibody neutralization and the efficient intercellular transmission of chikungunya virus in vitro and in vivo.

This study shows that a gut peptide is active against virulent forms of Candida albicans, thus contributing to the maintenance of fungal commensalism.

In this study, Huang et al. discover Delftia tsuruhatensis TC1, a mosquito symbiotic bacterium that inhibits parasite development via the secretion of a small molecule.

In this study, Sharafutdinov et al. report a single nucleotide polymorphism in the gene encoding the HtrA protease of Helicobacter pylori that is associated with gastric cancer.

This study shows that Haloferax volcanii uses its type IV pili for cell attachment to a surface and mechanical cohesion between cells under flow conditions, thus promoting biofilm development.

In this study, Gül et al. show that usage of different carbon sources by Enterobacteriaceae strains determines their expansion and co-existence in the mouse gut and favours plasmid transfer.

The study reveals how a satellite phage-encoded protein directs the assembly of coat proteins into small capsids.

In this study, Tsuji et al. report the glycolipid 7DW8-5 that exploits the host innate immune system to control SARS-CoV-2, respiratory syncytial virus and influenza virus infections.

The authors developed a refillable, long-acting subcutaneous nanofluidic antiretroviral delivery implant that conferred protection against infection with simian–human immunodeficiency virus in rhesus macaques.