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This month's Genome Watch highlights some of the technical challenges that need to be overcome to gain further insight into microbial metatranscriptomes.
This month's Genome Watch highlights how a population study, in conjunction with a reference genome, can identify the evolutionary features that contribute to drug resistance in a protozoan parasite.
This month's Genome Watch discusses the methods and implications of recent rapid sequence analyses of outbreak strains ofEscherichia coli and Vibrio cholerae.
Single-cell genomics, in which individual cells are isolated from environmental samples and their genomic DNA is sequenced, is increasingly used to characterize uncultivated microorganisms.
This month's Genome Watch looks at how recombination has providedStreptococcus pneumoniaewith the adaptability to overcome antibiotic and immune challenges.
Interest in the human intestinal microbiota has intensified in recent years, but research has been largely focused on bacteriology. This month's Genome Watch reviews a recent metagenomics study that instead aims to better characterize the viruses that inhabit our guts.
Following on from last month's discussion of sequence assembly and correction, this month's Genome Watch examines genome annotation in the context of advances in second-generation sequencing.