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In this Review, Georjon and Bernheim provide an overview of the molecular diversity of the most recently discovered bacterial antiphage defence systems and discuss their evolution and the ecological impact of their diversity.
In this Review, Langedijk and Bont discuss our current understanding of respiratory syncytial virus (RSV) burden of disease, virus biology and pathogenesis, and host and viral factors related to immunity as a segue towards the development of novel RSV interventions.
In this study, Gül et al. show that usage of different carbon sources by Enterobacteriaceae strains determines their expansion and co-existence in the mouse gut and favours plasmid transfer.
In this study, Tsuji et al. report the glycolipid 7DW8-5 that exploits the host innate immune system to control SARS-CoV-2, respiratory syncytial virus and influenza virus infections.
The authors developed a refillable, long-acting subcutaneous nanofluidic antiretroviral delivery implant that conferred protection against infection with simian–human immunodeficiency virus in rhesus macaques.
In this study, Irazoki et al. show that Vibrio cholerae releases d-amino acids into the environment, which are sensed by a bacterial chemoreceptor to prompt a repellent chemotactic response.
In this Review, Castañeda-Barba, Top and Stalder use the One Health framework to synthesize the recent literature on the ecological and evolutionary factors that determine the successful local and global spread of plasmid-mediated antimicrobial resistance genes.
In this Review, Porter and Sullivan examine how Wolbachia interact with diverse host cellular components driving the endosymbiont’s global spread and discuss strategies to exploit Wolbachia for insect-based and parasite-based disease control.
This study reports that human BTN3A3 restricts replication of avian influenza A viruses (IAVs) but not human IAVs, and that BTN3A3 evasion promotes spillover into humans.
In this Review, Xu, Gu and Lovley examine the varied mechanisms by which microorganisms can cause metal corrosion and explore different strategies that could prevent it.
In this Review, Landovitz, Scott and Deeks explore the current state of the art for HIV prevention and treatment, including unmet needs and emerging tools. They describe how researchers are combining different approaches, such as prevention, treatment and cure, to achieve better outcomes in the fight against the HIV/AIDS epidemic.
This study suggests that pre-existing DENV immunity has a negative effect on the pathogenesis of secondary ZIKV infection during pregnancy in marmosets.
The human microbiome has a crucial role in global health, with implications for achieving the Sustainable Development Goals (SDGs). Understanding and harnessing the potential of the microbiome, while recognizing its link to the global ecosystem, can drive innovative strategies for improved public health, and promote sustainable development.