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  • In this Review, Pai and colleagues examine the global landscape of drug-resistant tuberculosis, exploring its epidemiology, causes, risk factors, stigma and associated mental health burden as well as discussing the most recent developments in diagnostics, treatment and preventive regimens.

    • Maha Farhat
    • Helen Cox
    • Madhukar Pai
    Review Article
  • In this Review, Jiao, Robinson and colleagues examine recent advances related to the microbial carbon pump, exploring its role in the carbon cycle and climate change, and proposing future research directions and approaches to ocean negative carbon emissions.

    • Nianzhi Jiao
    • Tingwei Luo
    • Carol Robinson
    Review Article
  • In this Review, de Souza and Weaver discuss the potential effects on vector-borne diseases of climate change, weather and other anthropogenic factors, including land use, human mobility and behaviour, as possible contributors to the redistribution of vectors and spread of vector-borne diseases worldwide.

    • William M. de Souza
    • Scott C. Weaver
    Review Article
  • In this study, Armani-Tourret et al. show that the combination of panobinostat and pegylated interferon-α2a transforms the structure and composition of the HIV-1 reservoir and could potentially counter it.

    • Agustina Taglialegna
    Research Highlight
  • In this study, Liu et al. explore the interplay between a fungal effector and a plant cysteine protease and design a small-molecule compound aimed at targeting this effector to combat rice blast disease.

    • Agustina Taglialegna
    Research Highlight
  • In this Journal Club, Salvador Almagro-Moreno discusses a study by Kirn et al., which explores the emergence of virulence traits in Vibrio cholerae and demonstrates how the ability of this pathogen to colonize the host shares a common mechanism to its capacity to thrive in natural environments.

    • Salvador Almagro-Moreno
    Journal Club
  • In this Review, Voolstra, Raina, Peixoto and colleagues discuss our current knowledge of the function and role of the bacterial microbiome in coral health and disease, and elucidate the response of the host-associated bacteria to global change, which bears implications for coral reef conservation.

    • Christian R. Voolstra
    • Jean-Baptiste Raina
    • Raquel S. Peixoto
    Review Article
  • In this Review, Ledvina and Whiteley highlight the key similarities between eukaryotic and bacterial innate immune systems, exploring conserved immune components and signalling strategies, as well as conserved mechanisms for pathogen restriction.

    • Hannah E. Ledvina
    • Aaron T. Whiteley
    Review Article
  • Wastewater genomic surveillance can transform global viral disease monitoring. This Genome Watch article explores the techniques, analytical pipelines and implications for public health.

    • Arin Wongprommoon
    • Chalita Chomkatekaew
    • Claire Chewapreecha
    Genome Watch
  • In this study, Achberger et al. report that microbial communities of inactive hydrothermal deposits contribute to primary productivity in the deep sea.

    • Agustina Taglialegna
    Research Highlight
  • This month’s Genome Watch discusses the application of spatial transcriptomics to investigate the arrangements of microbial communities and their effects on the host.

    • Matthew J. Blow
    Genome Watch
  • The study provides insights into how insects and their endosymbionts can manipulate plant defences.

    • Andrea Du Toit
    Research Highlight