Browse Articles

Filter By:

  • A microfluidics study shows that bacterial biofilms form wrinkles when they grow and detach from a solid surface.

    • Ursula Hofer
    In Brief
  • Two recent studies highlight the potential of broadly neutralizing monoclonal antibodies for the long-term control of HIV in the absence of antiretroviral therapy.

    • Ashley York
    Research Highlight
  • A single-cell microfluidics study shows that phenotypic heterogeneity and fast growth can reduce antibiotic susceptibility.

    • Ursula Hofer
    In Brief
  • A study in hamsters shows prolonged inflammatory changes after COVID-19.

    • Ursula Hofer
    In Brief
  • A study in mice links a metabolite of the gut microbiota to age-related microglia death.

    • Ursula Hofer
    In Brief
  • A retrospective analysis of seven cases of monkeypox describes virus loads over time and looks at potential management options.

    • Ursula Hofer
    In Brief
  • An analysis of the economic impact of biofilms estimates it at almost US$4,000 billion per year globally.

    • Ursula Hofer
    In Brief
  • Trace metals are essential micronutrients required for survival across all kingdoms of life. In this Review, Murdoch and Skaar discuss the strategies whereby vertebrate hosts limit metal or induce excess metal to prevent bacterial proliferation, a process termed nutritional immunity, and they discuss adaptive mechanisms that bacterial pathogens have evolved to survive in conditions of metal depletion or excess.

    • Caitlin C. Murdoch
    • Eric P. Skaar
    Review Article
  • This study reports that a short prokaryotic argonaute protein from the archaeon Sulfolobus islandicus and its genetically associated proteins Aga1 and Aga2 confer antiviral defence by abortive infection.

    • Andrea Du Toit
    Research Highlight
  • Marine biofilms grow on diverse marine surfaces, ranging from particles to animals and ships. In this Review, Qian and colleagues discuss the diversity and composition of marine biofilms and their role in the development of marine benthos and biofouling.

    • Pei-Yuan Qian
    • Aifang Cheng
    • Rui Zhang
    Review Article
  • This study shows that upon urinary tract infections, uropathogenic Escherichia coli persist and subsequently adapt to the distinct physiological conditions encountered in the gastrointestinal and urinary environments.

    • Agustina Taglialegna
    Research Highlight
  • A study looking at the Tibetan Plateau finds that microbial shifts might contribute to irreversible soil degradation.

    • Ursula Hofer
    In Brief
  • This study used engineered bacteria to record the transcriptional responses of transiting bacteria in the gut environment.

    • Ursula Hofer
    In Brief
  • A study in mice shows that antibiotic treatment predisposes to invasive fungal infection through gut dysbiosis and barrier dysfunction.

    • Ursula Hofer
    In Brief
  • This Genome Watch highlights recently reported methods that enable genome editing of microorganisms within phylogenetically diverse communities.

    • Susannah G. Tringe
    Genome Watch
  • CRISPR–Cas systems provide resistance against foreign mobile genetic elements and have a wide range of genome editing and biotechnological applications. In this Review, Wang, Pausch and Doudna examine recent advances in understanding the molecular structures and mechanisms of enzymes comprising bacterial RNA-guided CRISPR–Cas immune systems and deployed for wide-ranging genome editing applications.

    • Joy Y. Wang
    • Patrick Pausch
    • Jennifer A. Doudna
    Review Article