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In this Review, McCallum and Tropini discuss physical and biological factors that affect microbiota biogeography and organization at different scales, starting with an overview of the whole gut at the macroscale and then zooming in to the scale of host and microbial interactions.
In this Journal Club, Gonzalo Moratorio discusses a study using deep mutational scanning (DMS) to uncover how the influenza virus evades the host immune response, highlighting the potential of DMS in understanding the evolutionary arms race between pathogens and hosts.
In this Journal Club, Anja Spang discusses the discovery of nanosized archaea, transforming our knowledge of archaeal phylogeny and shedding light on their roles in ecology and evolution.
In this Journal Club, Chelsey Spriggs discusses how the study of simian virus 40 (SV40) revealed a key sequence in the large T antigen that directs its transport into the cell nucleus, advancing our understanding of nuclear import mechanics.
In this Journal Club, Edmund Loh explores the pioneering work of Kurt Nordström and colleagues, which uncovers the importance of a small RNA in plasmid replication and elucidates its mechanism of action.
In this Journal Club, Lisa Maier explores Abigail Salyers’ groundbreaking research on Bacteroides thetaiotaomicron, focusing on how she established a new genetic system and investigated how these gut bacteria bind and use starch, uncovering important insights into their metabolism.
In this Journal Club, Rebecca Shapiro discusses the discovery of the earliest antifungal drug, nystatin, by pioneering women Elizabeth Hazen and Rachel Brown.
In this Journal Club, Tao Zuo discusses a study by Gogokhia et al. who found that gut bacteriophages can alter mucosal immunity to impact mammalian health.
In this Journal Club, Sarah Auburn discusses the pioneering development of the first framework for whole-genome sequencing of natural malaria infections, revolutionizing malaria genomics.
In this Review, He and co-workers explore the structure and diversity of the oral microbiota, and they discuss the role of the oral microbiota in the pathology of both oral and systemic diseases.
In this Review, Rillig, Kim and Zhu review our current understanding of the soil plastisphere, including the members of the microbial community that are enriched, the possible mechanisms underpinning this selection and functional properties.
In this Review, Lass-Flörl and Govrins explore the epidemiology, clinical manifestations and antifungal resistance of the Candida parapsilosis complex, and discuss diagnostics and new treatment approaches to tackle infections by these human pathogens.
This study shows that intercellular long extensions promote the evasion of antibody neutralization and the efficient intercellular transmission of chikungunya virus in vitro and in vivo.
This month’s Genome Watch highlights the use of high-depth genome-centric approaches to further our understanding of the human gut microbiome within the context of industrialized and non-industrialized lifestyles.
In this Review, Maillard and Pascoe examine the mechanisms of action of biocides, as well as the bacterial intrinsic and acquired resistance to these biocides and its implications in environmental and clinical settings.
In this Review, Lockhart, Chowdhary and Gold discuss the global emergence and spread of three emerging antifungal-resistant fungi: Candida auris, azole-resistant Aspergillus fumigatus and Trichophyton indotineae, with the common thread that all three are currently emerging across the globe and have a high rate of acquired resistance.
