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This study reports that some bacterial species of the Lachnospiraceae family can suppress colorectal cancer progression by modulating CD8⁺ T cell immune surveillance activity.

This study reports that heat treatment can increase the bactericidal activity of aminoglycosides against multi-drug resistant pathogens.

This study reports how fluid flow is linked to changes in gene expression in bacterial pathogens.

This study shows the development of a chimeric dengue virus bivalent vaccine that generated serotype-specific neutralizing antibodies in vivo.

A recent study uncovered a relationship between sensory neurons and immune cells in the meninges that facilitates brain invasion by two Streptococcus species and the development of meningitis in mice.

In this Review, Baldrian et al. discuss the effects of global change on the forest ecosystem and its microbiome across boreal, temperate and tropical climatic zones, and present different strategies aimed at reducing global change impact on forests.

This study reveals a role of contractile injection systems in regulated cell death and developmental processes.

This study analysed sorption, stability and persistence of SARS-CoV-2 RNA in sewers.

In this Review, Toyofuku, Schild, Kaparakis-Liaskos and Eberl discuss the different types of bacterial membrane vesicle, how they are formed, their structure and composition and their diverse functions.

This new study reports that a fungal ectosymbiont metabolizes resin monoterpenes of the host tree and that the volatile products possibly function as cues for beetles to locate breeding sites with beneficial fungal symbionts.

Crimean–Congo haemorrhagic fever (CCHF) is a severe and often lethal tick-borne illness that is caused by infection with the CCHF virus (CCHFV). In this Review, Hawman and Feldmann explore recent insights into the function of viral proteins in CCHFV pathogenesis, our current understanding of CCHF and the state of treatments and vaccines for CCHFV.

This Genome Watch highlights recent metagenomics studies in fish that reveal unique microbiomes with low functional diversity, which could help to improve our understanding of host–microorganism dynamics in non-mammalian species.

In this Review, Brouwer et al. summarize recent developments in our understanding of Group A Streptococcus (GAS), focusing on the epidemiologic and clinical features of GAS infection and the molecular mechanisms associated with GAS virulence and drug resistance.

In this Review, Lithgow and colleagues explore how imaging of the bacterial cell surface at nanoscale has revealed distinct zones and specific features, including functionally defined assembly precincts for protein insertion into the membrane and equivalent lipid-assembly precincts suggested from discrete lipopolysaccharide patches.

This study set out to increase our understanding of how viruses might mediate responses of microbial communities to climate warming.

This study evaluates the efficacy of exogenous pegylated IFNλ in the treatment of patients with COVID-19.

This study shows that the orphan kinesin KLIF is a non-processive dimeric kinesin that bundles microtubules in Trypanosoma brucei.

This Genome Watch explores how large-scale microbiome studies are facilitating discoveries in bacteriophage biology and functional capabilities that are prime for translation towards advances in biotechnology and biotherapeutics.

Vincent et al. investigate the impact of viral infection on the microbial communities of algal blooms and carbon cycling.

This study shows that Listeria monocytogenes and Enterococcus faecalis can evade phage predation by transient conversion to a cell wall-deficient L-form state.