Giant viruses

Giant virus biology and diversity in the era of genome-resolved metagenomics

  • Frederik Schulz
  • Chantal Abergel
  • Tanja Woyke
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  • This study reports that Enterococcus species can remodel the metabolic environment in the gut and reprogramme the metabolism of Clostridioides difficile, enhancing its fitness and virulence.

    • Agustina Taglialegna
    Research Highlight
  • This month’s Genome Watch highlights how genome sequencing can be used to understand the strain-level diversity, evolution and spatial structure of the human microbiome, and to inform therapeutic strategies.

    • Gemma G. R. Murray
    • Chrispin Chaguza
    Genome Watch
  • This study reports that the Chlamydia trachomatis effector TepP modulates epithelial tight junctions to promote infection.

    • Andrea Du Toit
    Research Highlight
  • This study characterized the role of periplasmic PgfA in mycobacterial growth and division.

    • Andrea Du Toit
    Research Highlight
  • This study reports the identification of a highly divergent lineage of SARS-CoV-2 in white-tailed deer and provides evidence of deer-to-human transmission.

    • Andrea Du Toit
    Research Highlight
  • A new study identified two distinct lineages of monkeypox virus (MPXV) in the United States with evidence of genome editing by host apolipoprotein B editing complex (APOBEC3) cytosine deaminase, which might be accelerating MPXV evolution.

    • Michael Attwaters
    Research Highlight
SARS-CoV-2 virions

COVID-19

The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has led to substantial disease and millions of deaths worldwide, with devastating socio-economic impacts. This Series contains articles from Nature Reviews Microbiology that explore the basic biology, epidemiology, emergence, evolution and pathogenesis of SARS-CoV-2 and pathogenic coronaviruses, as well as options for the control and prevention of COVID-19.
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