Targeting SARS-CoV-2

COVID-19 drug discovery and treatment options

  • Jasper Fuk-Woo Chan
  • Shuofeng Yuan
  • Kwok-Yung Yuen
Review Article


  • Logo Nature Awards Microbiome Accelerator

    The Accelerator will identify microbiome research with the potential to transform human health outcomes. Four carefully chosen applicants will be awarded $10,000 and gain entry to our immersive residential programme that provides the training/mentorship, and connections to translate groundbreaking research for maximum impact. Deadline for applications is 24 June 2024.


  • In this study, Diehl et al. report that brilacidin could be a promising antifungal drug against Cryptococcus neoformans.

    • Agustina Taglialegna
    Research Highlight
  • In this study, White et al. report that Alcaligenes faecalis mediates wound repair in diabetic foot ulcers.

    • Agustina Taglialegna
    Research Highlight
  • A WHO report suggests the terms ‘airborne transmission/inhalation’, ‘direct deposition’ and ‘infectious respiratory particles’ for describing transmission modes, highlighting the continuum of particle size with greatest exposure near the source. The report did not update infection control guidelines.

    • Nancy H. L. Leung
    • Donald K. Milton
  • In this study, Hiis et al. demonstrate that the N2O-respiring bacterial strain Cloacibacterium sp. CB-01 can reduce nitrous oxide emissions from soil.

    • Agustina Taglialegna
    Research Highlight
  • This study shows that archaea produce catalytically active ultraminimal as well as hybrid [FeFe] hydrogenases.

    • Andrea Du Toit
    Research Highlight
SARS-CoV-2 virions


The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has led to substantial disease and millions of deaths worldwide, with devastating socio-economic impacts. This Series contains articles from Nature Reviews Microbiology that explore the basic biology, epidemiology, emergence, evolution and pathogenesis of SARS-CoV-2 and pathogenic coronaviruses, as well as options for the control and prevention of COVID-19.


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