Volume 12 Issue 4, April 2011

From The Editors

Research Highlights


  • Review Article |

    Shoot branching is regulated by three classes of plant hormones, auxins, strigolactones (or derivatives) and cytokinins. In the past decade, two models — the auxin transport canalization-based model and the second messenger model — have been formulated to explain the mechanisms of bud activation and shoot branching control.

    • Malgorzata A. Domagalska
    •  & Ottoline Leyser
  • Review Article |

    Cilium assembly requires the coordination of motor-driven intraflagellar transport, membrane trafficking and import of cilium-specific proteins through a barrier at the ciliary transition zone. Recent findings provide insights into how cilia might assemble and disassemble in synchrony with the cell cycle and achieve a steady-state length.

    • Hiroaki Ishikawa
    •  & Wallace F. Marshall
  • Review Article |

    The initiation of translation in eukaryotes can be impeded by secondary structures in the mRNA upstream of the initiation codon. There is increasing evidence that several helicases act in concert to overcome such structures and to promote processive movement of the 40S ribosome subunit.

    • Armen Parsyan
    • , Yuri Svitkin
    • , David Shahbazian
    • , Christos Gkogkas
    • , Paul Lasko
    • , William C. Merrick
    •  & Nahum Sonenberg
  • Review Article |

    The genome encodes thousands of small RNAs that interact with PIWI proteins; these PIWI-interacting RNAs (piRNAs) mediate silencing of transposable elements and thereby protect the genome. New insights are being gained into the formation and functions of piRNAs, and where they exert their action in the cell.

    • Mikiko C. Siomi
    • , Kaoru Sato
    • , Dubravka Pezic
    •  & Alexei A. Aravin



  • Opinion |

    The p53 family of transcription factors have diverse roles during development and in cancer. However, there is increasing evidence that their ancestral function may have been to regulate unique aspects of maternal fertility.

    • Arnold J. Levine
    • , Richard Tomasini
    • , Frank D. McKeon
    • , Tak W. Mak
    •  & Gerry Melino
  • Opinion |

    Computational morphodynamics has provided great insights into the highly dynamic process of plant development. This is because it combines live imaging to observe development as it happens, image processing to extract data, and computational modelling to test hypotheses against quantitative information.

    • Adrienne H. K. Roeder
    • , Paul T. Tarr
    • , Cory Tobin
    • , Xiaolan Zhang
    • , Vijay Chickarmane
    • , Alexandre Cunha
    •  & Elliot M. Meyerowitz