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This Comment draws attention to cellular protrusions as a source of extracellular vesicles (EVs). These protrusion-derived vesicles expand the repertoire of EVs, impacting current nomenclature and our understanding of EV functions in inter-cellular communication.
Bishop and Hawley argue against a direct relationship between changes in mRNA levels and the abundance of the proteins they encode in skeletal muscles in response to exercise.
Kempson and colleagues suggest that existing imaging assays do not quantitatively represent double-strand DNA breaks, and urge the development of more accurate assays.
Olivier Voinnet proposes that movement of gene-silencing small RNAs (sRNAs) in plants can be regulated by intracellular sRNA biogenesis and activity factors expressed in silencing-signal emitting, traversed and recipient cells.