Journal Clubs

Our knowledge of autophagy has taken several 'quantum leaps' since the term was coined by Christian de Duve.

In 2008, the Bankaitis group suggested that lipid transport proteins can exchange one membrane lipid for another.

Three-dimensional trajectories of chromatin have been visualized by Hi-C.

The sixtieth anniversary of the 'stem cell renewal theory' by Yves Clermont and Charles Philippe Leblond.

The discovery of tubulin modification by Tyr.

The first chaperonin was discovered in plants in 1980.

The studies that implicated CIN and aneuploidy in ageing.

Experiments using SRC led to the discovery of focal adhesion kinase and the catenin p120ctn.

The discovery that GSK3β is a target of lithium.

The identification of XBP1 as the target of IRE1α in the UPR.

Multipotent stem and progenitor cells are heterogeneous in lineage choice and timing of commitment to differentiation.

The timing of DNA replication might have a role in establishing cell identity during development.

Simple experiments demonstrated that auxin transport, which is important to plant development, self-organizes.

The demonstration that senescence is caused by both telomere erosion and oncogene-induced accumulation of DNA damage at telomeres.

Dying cells promote the proliferation of neighboring cells and thus promote tissue growth.

The demonstration of yeast fermentation laid the foundations for cell-free assays.

Clues into how newly formed procentrioles emerge at a right angle from the mother centriole.

Conly Rieder and colleagues demonstrated in 1995 that one unattached chromosome is sufficient to prevent sister chromatid separation in mitosis.

Studies in the late nineteenth century showed that both the sperm and the egg contribute to the generation of new life.

Two studies identify aldehyde metabolites as a potential endogenous source of ICLs.