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  • Paul Nurse discusses how a 1971 paper by Culotti and Hartwell inspired him to investigate the cell cycle in fission yeast, and how these genetics studies led to the discovery of cyclin-dependent kinases.

    • Paul Nurse
    Journal Club
  • The studies that paved the way for the development of PROTACs (proteolysis-targeting chimeras) as therapeutic strategies, and the HPV vaccine.

    • Kylie J. Walters
    Journal Club
  • Many proteins in the mouse ovary are extremely stable; they enhance proteostasis and limit protein aggregation, thereby supporting the maintenance of the long-lived oocytes.

    • Eytan Zlotorynski
    Research Highlight
  • In a recent study, Bong et al. identify a polarized distribution of contact sites between the endoplasmic reticulum and plasma membrane in migrating cells, whereby higher density of contacts in the back of the cells prevents the formation of additional migration fronts.

    • Lisa Heinke
    Research Highlight
The sea with lipid rafts

Lipids and membranes

This article series brings together Reviews that focus on key advances in understanding membrane biology as well as the regulation and functions of their lipid components, including their roles as bioactive molecules and their interplay with metabolism.
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