Journal Clubs in 2018

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  • Laura Mackay describes two landmark papers by Gebhardt et al. and Masopust et al., published in 2009 and 2010, that signified the advent of tissue-resident memory T cells as a distinct T cell subset.

    • Laura K. Mackay
    Journal Club
  • Adrian Liston describes two papers by Nicole Le Douarin and colleagues from the 1980s that used a chick–quail graft system to show the existence of dominant T cell tolerance.

    • Adrian Liston
    Journal Club
  • Jeffrey Bluestone describes a 1987 study of anergic T cells by Marc Jenkins and Ron Schwartz that altered his thoughts about T cell tolerance and eventually gave birth to the field of checkpoint inhibition.

    • Jeffrey A. Bluestone
    Journal Club
  • Thirumala-Devi Kanneganti describes a 2002 study by Jürg Tschopp and colleagues that first described the multiprotein, caspase-activating inflammasome complex that drives the maturation and secretion of IL-1β.

    • Thirumala-Devi Kanneganti
    Journal Club
  • Gabrielle Belz describes a 2002 paper by Iyer et al. that linked cellular nutrient levels in cytotoxic T cells with their ability to mount a vigorous response.

    • Gabrielle Belz
    Journal Club
  • Jean-Laurent Casanova describes three papers by Max Cooper and colleagues that described the convergent evolution of adaptive immunity in jawless vertebrates.

    • Jean-Laurent Casanova
    Journal Club
  • Jedd Wolchok describes a 1996 study by Alan Houghton and colleagues that showed how immune tolerance to self antigens on cancer cells could be overcome.

    • Jedd D. Wolchok
    Journal Club