Announcements

  • Picture of coronavirus

    NRI is 20! To celebrate this milestone, we present 20 Journal Club articles that pay tribute to some of the major immunological breakthroughs that have occurred since the journal was launched in October 2001. We also announce the launch of a new series of Perspective articles that consider the ‘past, present and future’ use of immunotherapies in different disease settings.

  • Neuroimmune Series

    The field of neuroimmunology has blossomed in recent years. This can be attributed to sophisticated technological advances as well as to the burgeoning collaboration of neuroscientists and immunologists. Articles in this Series reflect the fruits of these collaborative efforts and review our current understanding of the intricate crosstalk that takes place between the immune and nervous systems.

  • Picture of peer review

    In this Collection, we bring you articles that highlight the latest research and insight into the immunology of SARS-CoV-2 and the associated disease COVID-19. They cover our emerging understanding of the immune response to this new coronavirus, prospects for vaccine development, immunopathology of COVID-19 and how it might be treated with immunomodulatory drugs.

  • A regularly updated list of upcoming immunology conferences, including virtual meetings

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    • The ancestral strain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into a number of variants of concern. In this Review, Wang and colleagues discuss progress in the development and characterization of broadly neutralizing antibodies to SARS-CoV-2, which may lead to new antibody therapeutics and inform the design of next-generation vaccines.

      • Yanjia Chen
      • Xiaoyu Zhao
      • Pengfei Wang
      Review Article
    • Three-dimensional (3D) genome organization has emerged as an important regulator of gene expression and genomic interaction. Here, the authors explain how 3D genome organization impacts immune cell development and function, and discuss how aberrant genome folding can contribute to immune-mediated disease and cancer.

      • Sergi Cuartero
      • Grégoire Stik
      • Ralph Stadhouders
      Review Article
    • In this Review, Ng and colleagues examine the clinical, epidemiological and immunological aspects of monkeypox virus (MPXV) infections, with a focus on mechanisms of host immunity to MPXV. The authors also consider the unique epidemiological and pathological characteristics of the current non-endemic outbreak of the virus and discuss vaccines, therapeutics and outstanding research questions.

      • Fok-Moon Lum
      • Anthony Torres-Ruesta
      • Lisa F. P. Ng
      Review Article
    • This Review considers how the biophysical properties of a tissue are able to shape immune cell function through the process of mechanotransduction. There are multiple mechanotransduction pathways that operate in immune cells and the authors highlight these and the emerging field of mechanoimmunology.

      • Huixun Du
      • Juliet M. Bartleson
      • Manish J. Butte
      Review Article
    • There are many reasons why the development of a potent and durable vaccine to HIV-1 is exceptionally challenging, including the large genetic diversity of the virus and its complex mechanisms of immune evasion. In this Review, Haynes et al. discuss strategies for the induction of potent broadly neutralizing antibodies for HIV-1 and the steps that may be necessary for ultimate success.

      • Barton F. Haynes
      • Kevin Wiehe
      • George M. Shaw
      Review Article
Neuroimmune connections

Neuroimmunology

A Series of articles published in Nature Reviews Immunology focusing on connections between the immune system and nervous system.
  • Lucy Bird
Series

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