wallpaper showing pattern of spleens

Splenic stromal niches

Splenic stromal niches in homeostasis and immunity


  • Picture of T cell and antigen-presenting cell

    The 2023 Nobel prize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their “discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19”. In this Collection, Nature Portfolio recognizes the achievements of the Nobel Laureates in a selection of research, review, news and opinion articles.

  • Picture of T cell and antigen-presenting cell

    In the 1950s and 1960s, scientists performed experiments to follow lymphocytes on their journey around the body, which helped us to work out where they go and what they do. This work laid the foundation for everything we know about T cells today, including how they become activated to fight infections and how they form memory populations that provide long-lasting immunity.

  • Picture of peer review

    In this Collection, we bring you articles that highlight the latest research and insight into the immunology of SARS-CoV-2 and the associated disease COVID-19. They cover our emerging understanding of the immune response to this new coronavirus, prospects for vaccine development, immunopathology of COVID-19 and how it might be treated with immunomodulatory drugs.

  • A regularly updated list of upcoming immunology conferences, including virtual meetings


    • In this Review, Butterfield and Najjar discuss the rationale for combination strategies in cancer, including combinations of different immunotherapies and combinations of immunotherapies with other types of therapies. Moreover, they examine the evolution of biomarker approaches to guide such therapies.

      • Lisa H. Butterfield
      • Yana G. Najjar
      Review Article
    • In this Review, Liston et al. discuss the biology of regulatory T cells (Treg cells) in the brain. They consider how Treg cells are recruited to the brain and their anti-inflammatory and reparative functions in brain tissue. Finally, they highlight the potential for targeting brain Treg cells to treat a range of neurological diseases.

      • Adrian Liston
      • Emanuela Pasciuto
      • Lidia Yshii
      Review Article
    • This Review outlines the mechanisms by which the microbiota alters the efficacy and immunotoxicity of established and emerging cancer treatments, and discusses the benefits and limitations of microbiota-targeting interventions that are being investigated to improve patient outcomes.

      • Stephen J. Blake
      • Yochai Wolf
      • David J. Lynn
      Review Article
    • Epidemiological studies and mouse models suggest that stress can affect the evolution, dissemination and outcome of malignancies. In this Review, Ma and Kroemer present insights into the complex neuro-immune interactions that link stress to cancer, with a focus on stress-associated immunomodulatory molecules, and discuss their implications for cancer therapy.

      • Yuting Ma
      • Guido Kroemer
      Review Article
    • In this Perspective, the authors consider the distinct contributions made by T helper 2 cells and group 2 innate lymphoid cells during the course of a helminth infection. Although anti-helminth drugs are effective, reinfection is common and there are currently no available vaccines — a better understanding of T helper 2 cell and group 2 innate lymphoid cell interplay could lead to new anti-helminth strategies.

      • Dietmar M. W. Zaiss
      • Edward J. Pearce
      • Christoph S. N. Klose
Neuroimmune connections


A Series of articles published in Nature Reviews Immunology focusing on connections between the immune system and nervous system.
  • Lucy Bird


Nature Careers

Science jobs