Volume 4 Issue 10, October 2007



  • Viewpoint |

    Convincing new evidence suggests that mild hypothermia prevents intracranial hypertension and its complications in patients with acute liver failure. This Viewpoint examines available data for the use of mild hypothermia as a novel therapy in this setting, and calls for controlled clinical trials and systematic studies of its potential adverse effects.

    • Javier Vaquero
    •  & Roger F Butterworth
  • Viewpoint |

    Chronic pancreatitis is a difficult disease to diagnose, particularly in its early stages. EUS has been increasingly used as a method for diagnosing chronic pancreatitis because of its ability to generate high-resolution images of the pancreas. This Viewpoint examines the practical role of EUS as screening tool for chronic pancreatitis, and compares it with other diagnostic modalities.

    • Massimo Raimondo

Research Highlights

Practice Points


  • Review Article |

    Rectal prolapse causes significant discomfort because of the sensation of the prolapse itself, the mucus that it secretes, and because it tends to stretch the anal sphincters and cause incontinence. Treatment is primarily surgical; however, there are different opinions about which type of surgical repair is best. The authors of this Review discuss the pathogenesis, clinical presentation, evaluation and surgical management of rectal prolapse.

    • Eric L Marderstein
    •  & Conor P Delaney
  • Review Article |

    Although the incidence of stress-induced gastrointestinal bleeding has decreased, such bleeding is associated with increased morbidity and mortality in critically ill patients. In this Review, the authors address some of the issues surrounding treatment for the prevention of stress-induced gastrointestinal bleeding, such as whether all patients need prophylaxis, and how long prophylaxis should be continued for.

    • Frank H Klebl
    •  & Jürgen Schölmerich
  • Review Article |

    Colonoscopy is increasingly being used for colorectal cancer screening, which has resulted in a growing cohort of patients who have polyps and require postpolypectomy surveillance. In this Review, the authors present an overview of the new postpolypectomy surveillance guidelines, explain the rationale behind them, discuss barriers to their implementation, and examine strategies to overcome these barriers.

    • Charles J Kahi
    •  & Douglas K Rex

Case Study