Nature Reviews Gastroenterology & Hepatology

The four epidemiological stages in the global evolution of inflammatory bowel disease

Gilaad G. Kaplan
Joseph W. Windsor

Perspective 08 October 2020

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Transcriptional programmes underlying cellular identity and microbial responsiveness in the intestinal epithelium

Transcriptional regulatory mechanisms have a dual role in specifying intestinal epithelial identity and enabling microbial responsiveness. In this Review, Rawls and colleagues describe what is currently known about the epigenetic patterning and transcription factors responsible for this duality.
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Review Article 06 Oct 2020

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News & Comment

Point-of-care intestinal ultrasonography in inflammatory bowel disease

Intestinal ultrasonography (IUS) is an emerging, noninvasive, highly accessible and low-cost cross-sectional imaging modality for inflammatory bowel disease. This Comment summarizes how IUS in a point-of-care setting enables close patient monitoring.
Floris A. E. de Voogd
Bram Verstockt
Krisztina B. Gecse

Comment 27 Jan 2021
Liver metastases siphon T cells and blunt immunotherapy responses
Iain Dickson

Research Highlight 25 Jan 2021
SARS-CoV-2 vaccination in IBD: more pros than cons

Data on the efficacy and safety of SARS-CoV-2 vaccines are now available, but evidence for these vaccines in those who are immunocompromised (including patients with inflammatory bowel diseases) are lacking. As vaccination begins, questions on advantages and disadvantages can be partially addressed using the experience from other vaccines or immune-mediated inflammatory disorders.
Ferdinando D’Amico
Christian Rabaud
Silvio Danese

Comment 20 Jan 2021
Full-spectrum transcriptomics in NAFLD
Iain Dickson

Research Highlight 13 Jan 2021
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