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Practitioners in the field of single-cell omics are now faced with diverse options for analytical tools to process and integrate data from various molecular modalities. In an Expert Recommendation article, the authors provide guidance on robust single-cell data analysis, including choices of best-performing tools from benchmarking studies.
Cell fusion models containing genomes from different cell types or species in a single nucleus offer unique research benefits. Here, Pavlovic et al. advocate against describing such models as hybrids and propose a new nomenclature for interspecies cell fusions that lacks reproductive connotations.
In this Expert Recommendation, the authors review the definitions of classic concepts relating to bacterial gene regulation, with a focus on transcription initiation, and suggest up-to-date, precise definitions to provide a reference for knowledge representation, modelling and future research on bacterial gene regulation.
