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October 2020 marks the 20th anniversary of the launch of Nature Reviews Genetics. To celebrate this milestone, we have delved into our archives to curate a Collection of cutting-edge articles, historical pieces and thought-provoking commentaries and opinions. Featuring a range of article types, including Reviews, Perspectives, Viewpoints and Comments, this Collection provides a glimpse of the genetics and genomics field over the past two decades.
To support urgent research to combat the ongoing outbreak of COVID-19, caused by the novel coronavirus SARS-CoV-2, the editorial teams at Nature Research have curated a collection of relevant articles.
This collection includes recent articles from across the Nature group of journals and showcases both the latest advances in the methodologies used to study genome organization, and our recent understanding of how genome organization and nuclear architecture regulate gene expression, cell fate and cell function in physiology and disease.
In this Focus issue on microbial genomics, Nature Reviews Genetics explores the impact of high-throughput sequencing technologies on microbiology research and their emerging application in clinical practice.
This collection combines published Research articles and Reviews from several Nature journals highlighting recent advances in our understanding of the role of the gut microbiota in health and disease, and the tools for studying these complex communities.
Autoimmunity is an underlying cause of many diseases. This collection of Research, Reviews and News articles from several Nature journals covers the latest advances in genetic and epigenetic research into autoimmunity and autoimmune diseases.
Stem cells are well on their way into the clinic and can be used in a variety of applications, such as disease modelling, drug screening and for regenerative medicine. This collection showcases research articles, reviews and protocols from across the Nature journals to highlight the striking advances made in basic and translational stem cell research.
Recent technological advances are providing unprecedented opportunities to analyse the complexities of biological systems at the single-cell level. Various crucial biological phenomena are either invisible or only partially characterized when interrogated using standard analyses that average data across a bulk population of cells. However, high-throughput analyses of the genomes, transcriptomes and proteomes of single cells are providing novel and important insights into diverse processes such as development, gene-expression dynamics, tissue heterogeneity and disease pathogenesis.
With improved methods to explore the transcriptome, in recent years there have been great advances in identifying and understanding non-coding RNAs. Regulatory pathways involving small RNAs, such as microRNAs, are now being elucidated in detail, and functions for long non-coding RNAs are also coming to light. The articles in this series discuss insights into the biology of non-coding RNAs of all sizes in a wide range of organisms.