Different coloured fireworks consisting of single cells

A focus on single-cell omics

In this Focus issue and its accompanying online collection, we delve into the exciting developments in single-cell omics, highlighting its transformative potential.


  • Stylized multi-coloured Circos plot

    Gregor Johann Mendel, considered by many the ‘father of modern genetics’, was born 200 years ago, on 20 July 1822. In commemoration of this milestone, this Nature Collection brings together articles that explore the origins of genetics and reflect on Mendel’s legacy, which continues to shape the field to this day.

  • A snapshot of a circos plot

    The advent of massively parallel sequencing technologies has driven the analysis of cancer genomes at an unprecedented resolution. Next-generation sequencing has also been applied to study the epigenomes and transcriptomes of cancer, thus paving the way for an integrated understanding of cancer pathology.

  • Nature Reviews Genetics logo

    The editors of Nature Reviews Genetics will be posting about the latest developments in research and policy, and providing news about the journal. If you have any questions or feedback for us, get in touch by email or on Twitter.

  • Researchers stranded on an island

    Finding it hard to navigate the flood of scientific literature? The Nature Reviews journals filter and highlight the most impactful research. Take a look at this animation to learn how Nature Reviews Genetics can help you stay up-to-date, or visit www.springernature.com/naturereviews


  • Guhlin et al. sequenced the genomes of almost the entire extant population of the critically-endangered kākāpō, revealing genetic variants for fitness-related traits that can inform conservation strategies.

    • Michael Attwaters
    Research Highlight
  • Luis Barreiro highlights a 2007 paper by Tishkoff et al. that identified genetic variants associated with lactose persistence in East African populations, representing one of the first examples of convergent evolution in humans.

    • Luis B. Barreiro
    Journal Club
  • Marnie Blewitt highlights the visionary 1961 paper by Mary Lyon in which she proposed that dosage compensation in female mammals involves X-inactivation and recognized its implications for sex-specific phenotypes in X-linked disorders.

    • Marnie E. Blewitt
    Journal Club
An image that echoes the SDG logo and integrates the idea of analysis of data from the various goals.

Progress towards the Sustainable Development Goals

The year 2023 marks the mid-point of the 15-year period envisaged to achieve the Sustainable Development Goals, targets for global development adopted in September 2015 by all United Nations Member States.
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