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Spatial omics profiling technologies

Emerging spatial omics methods enable the charting of cellular heterogeneity, complex tissue architectures and dynamic changes during development and disease

  • Jeffrey R. Moffitt
  • Emma Lundberg
  • Holger Heyn
Review Article

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Colourful exploding fireworks, made up of on individual single cells, on a black background

Single-cell omics

Many biological phenomena are either invisible or only partially characterized when interrogated using standard analyses that average data across a bulk population of cells. Now, technological advances are providing unprecedented opportunities to analyse the complexities of biological systems at the single-cell level. High-throughput analyses of the genomes, transcriptomes and proteomes of single cells are yielding novel and important insights into diverse processes such as development, gene-expression dynamics, tissue heterogeneity and disease pathogenesis. In this Focus issue, we highlight the transformative potential of single-cell omics approaches.
  • Linda Koch
Focus

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