Clock face showing healthy and degrading cells outside and molecular components inside

Measuring biological age using omics data

  • Jarod Rutledge
  • Hamilton Oh
  • Tony Wyss-Coray
Review Article


  • Stylized multi-coloured Circos plot

    Gregor Johann Mendel, considered by many the ‘father of modern genetics’, was born 200 years ago, on 20 July 1822. In commemoration of this milestone, this Nature Collection brings together articles that explore the origins of genetics and reflect on Mendel’s legacy, which continues to shape the field to this day.

  • Immune cells attacking cancer cells

    The immune system is constantly on the lookout for threats but can fail to spot cancer. Now, advanced sequencing technologies are enabling scientists to investigate the unique genetics of both cancers and immune responses in individual patients. This means researchers can develop treatments that boost the immune system and help the body win its battle against cancer.

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    The editors of Nature Reviews Genetics will be posting about the latest developments in research and policy, and providing news about the journal. If you have any questions or feedback for us, get in touch by email or on Twitter.

  • Researchers stranded on an island

    Finding it hard to navigate the flood of scientific literature? The Nature Reviews journals filter and highlight the most impactful research. Take a look at this animation to learn how Nature Reviews Genetics can help you stay up-to-date, or visit


  • A new paper in Science reports that human genomes encode a large repertoire of retroviral envelope-derived proteins, with potential roles in protecting from infection by other retroviruses.

    • Darren J. Burgess
    Research Highlight
  • A microscopy-based pooled CRISPR screening approach described in Cell enables the cellular functions of thousands of genes to be assessed at remarkable phenotypic depth.

    • Dorothy Clyde
    Research Highlight
  • A new study in Science reports the refactoring of genetic codes in Escherichia coli to create a bidirectional ‘genetic firewall’ that prevents genetic transfer from or to synthetic organisms.

    • Kirsty Minton
    Research Highlight
  • A new study reports Epigenomic MERFISH, an imaging method that combines CUT&Tag and MERFISH to interrogate histone marks representing cis-regulatory elements in single cells while preserving spatial information.

    • Linda Koch
    Research Highlight
  • A new study in Cell describes how topologically associating domains (TADs) of chromosomes can restructure to resolve the regulatory conflict that arises when a new gene incorporates into an ancestral TAD.

    • Darren J. Burgess
    Research Highlight
A Nobel Prize medal against a background of pills and an electrocardiogra

Nobel Prize in Physiology or Medicine 2022

The 2022 Nobel Prize in Physiology or Medicine was awarded to Svante Pääbo "for his discoveries concerning the genomes of extinct hominins and human evolution".


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