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Measuring biological age using omics data

  • Jarod Rutledge
  • Hamilton Oh
  • Tony Wyss-Coray
Review Article

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  • A new study in Nature Methods describes a computational method named UTAG (unsupervised discovery of tissue architecture with graphs) that aims to identify and quantify higher-level tissue domains from biological images without previous knowledge.

    • Linda Koch
    Research Highlight
  • Riccardo Marioni discusses how the publication of Horvath’s epigenetic clock has affected research into ageing, rejuvenation and epigenetic epidemiology.

    • Riccardo E. Marioni
    Journal Club
  • Luis Saraiva recalls a 1997 paper by Krings et al., which reports the sequencing of mitochondrial Neanderthal DNA extracted from a 40,000-year-old bone, enabling the direct study of the relationship between ancient and modern humans.

    • Luis R. Saraiva
    Journal Club
  • A new paper in Science reports that human genomes encode a large repertoire of retroviral envelope-derived proteins, with potential roles in protecting from infection by other retroviruses.

    • Darren J. Burgess
    Research Highlight
  • A microscopy-based pooled CRISPR screening approach described in Cell enables the cellular functions of thousands of genes to be assessed at remarkable phenotypic depth.

    • Dorothy Clyde
    Research Highlight
A Nobel Prize medal against a background of pills and an electrocardiogra

Nobel Prize in Physiology or Medicine 2022

The 2022 Nobel Prize in Physiology or Medicine was awarded to Svante Pääbo "for his discoveries concerning the genomes of extinct hominins and human evolution".
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