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The symptoms of long COVID and chronic adrenal insufficiency have striking similarities. Therefore, we aim to raise awareness of assessing adrenal function in patients with long COVID.
From April 2022, as part of the UK government’s new obesity strategy, it is now compulsory for all larger restaurant and cafes in the UK to include calorie labelling on their menus. Is this legislation, however, likely to be effective in reducing our caloric intake, thereby tackling obesity?
A recent study has generated compelling experimental data on the role of GPR177 and WNT5a in the pathogenesis and treatment of painful diabetic neuropathy (PDN). The clinical value of these translational findings should be interpreted with caution. However, the limited efficacy of current treatments for PDN warrants further clinical studies on these novel pathways.
Macrophages in the liver can undergo phenotypic changes during metabolic diseases such as non-alcoholic fatty liver disease (NAFLD). This Review discusses our current understanding of the changes in the proportions and functions of liver macrophage populations in health and NAFLD.
This Review considers the principal regulators of the processes of biomineralization and crystallization in human physiology. In addition, disorders of biomineralization are discussed, including bone disorders and disorders of extraskeletal mineralization.
Menopause affects roughly half of the global population, yet many affected people do not receive the treatment they need. This Review discusses currently available menopausal hormonal therapies and novel pharmaceutical alternatives to manage menopausal symptoms.
This Review highlights evidence that persistent enterovirus infections, particularly coxsackievirus B, trigger and/or accelerate islet autoimmunity in susceptible individuals, thereby leading to type 1 diabetes mellitus (T1DM). The potential for vaccination or antiviral therapies to prevent T1DM onset is also considered.
