The December issue includes Reviews on fatty acid oxidation in skeletal muscle, stress kinases in metabolic disease and determining HbA1c targets for diabetes mellitus, as well as a Perspective on circadian rhythms and the gut microbiota.

The November issue includes a collection of six Comment articles celebrating our 15th anniversary, Reviews on DPP4 inhibitors, immunotherapy for thyroid cancer and the therapeutic potential of FGF21, as well as a Perspective on lipoedema.

The October issue includes Reviews on diet and exercise in the prevention and treatment of type 2 diabetes mellitus, SGLT2 inhibitors in the treatment of type 2 diabetes mellitus, the pathogenesis and treatment of primary aldosteronism and precision medicine for neuroendocrine neoplasia of the gastrointestinal tract.

The September issue includes Reviews on placental development, exercise adaptations, methods to generate functional β-cells and epigenetic factors that affect reproductive function, as well as two Comment articles on fragility fractures and obesity during the COVID-19 pandemic.

The August issue includes an Evidence-based Guideline on the diagnosis and management of dumping syndrome, as well as Reviews on metabolic regulation of kisspeptin, creatine metabolism and the pathogenesis and treatment of glucocorticoid-induced osteoporosis.

The July issue includes a Comment on COVID-19 and obesity, Reviews on β-cell failure in diabetes mellitus, nuclear receptor crosstalk and neonatal diabetes, and a Perspectives on lifestyle-based prevention of type 2 diabetes mellitus.

The June issue includes Reviews on the role of macronutrients in obesity and young-onset type 2 diabetes mellitus, as well as a Perspective on interventions for preventing fractures in postmenopausal women with osteoporosis.

The May issue includes Reviews on the role of cellular senescence in ageing and endocrine disease, insulin–PI3K signalling as a metabolic driver of cancer and 11-oxygenated androgens in health and disease.

The April issue includes Reviews on the genetics of type 2 diabetes mellitus, the role of food as a circadian time cue, ceramides in metabolic disorders and vitamin D metabolism and action.

The March issue includes a Consensus Statement on use of waist circumference measurements in clinical practice. This issue also includes Reviews on the effects of growth hormone in adipose tissue, the role of thyroid hormones in craniofacial development and the physiological functions of selenium.

The February issue includes five Year in Review articles that summarise advances from the past year in key areas of endocrinology. Also included are Reviews on islet inflammation, genetics of osteoporosis and Graves orbitopathy and a Perspectives on tackling the obesity epidemic.

The January issue includes a Consensus Statement on how to define endocrine-disrupting chemicals, a Perspective on the implications of high protein intake and Reviews on the global rise of thyroid cancer and the crosstalk between adipocytes and immune cells.