Susanne Harris

Caring for individuals with a difference of sex development (DSD): a Consensus Statement

This Consensus Statement by Martine Cools and colleagues summarizes recommendations for clinical indications, diagnosis and management of patients with differences of sexual development.

Latest Reviews

  • Review Article |

    The liver X receptor (LXR) pathway is important for maintaining cholesterol homeostasis. In this Review, the authors discuss the role of LXRs in cholesterol and lipid metabolism and the emerging strategies to target the LXR pathway to treat metabolic diseases.

    • Bo Wang
    •  & Peter Tontonoz
  • Perspective |

    Unhealthy food and drink surround us in our daily food environments. Here, Anna Peeters discusses how we can improve our food environments and details how clinicians can help implement and set healthy food policies across all our health-care settings.

    • Anna Peeters
  • Review Article |

    The δ-cells of the pancreatic islets secrete somatostatin, which inhibits insulin and glucagon secretion. In this Review, the authors summarize the cellular physiology of somatostatin secretion, how this might go wrong in diabetes mellitus and potential therapeutic targets.

    • Patrik Rorsman
    •  & Mark O. Huising
  • Consensus Statement | | open

    Differences of sex development (DSDs) comprise a large group of congenital conditions of the urogenital tract and reproductive system. This Consensus Statement summarizes recommendations for clinical indications, diagnosis and management of patients with a DSD.

    • Martine Cools
    • , Anna Nordenström
    • , Ralitsa Robeva
    • , Joanne Hall
    • , Puck Westerveld
    • , Christa Flück
    • , Birgit Köhler
    • , Marta Berra
    • , Alexander Springer
    • , Katinka Schweizer
    •  & Vickie Pasterski
  • Review Article |

    In this Review, the authors describe the physiology of glucagon-like peptide 1 (GLP1) and its role in type 2 diabetes mellitus (T2DM), the currently available and emerging GLP1 receptor agonists and their use to treat T2DM and other indications.

    • Andreas Andersen
    • , Asger Lund
    • , Filip K. Knop
    •  & Tina Vilsbøll
  • Review Article |

    This Review focuses on the emerging preclinical evidence implicating alterations in autophagy as a pathophysiological mechanism underpinning the development of obesity and its complications. The therapeutic potential of pharmacological and nonpharmacological modulation of autophagy in obesity and its sequelae is also discussed.

    • Yingmei Zhang
    • , James R. Sowers
    •  & Jun Ren

News & Comment

Collection

Key Advances in Medicine 2018

Much like our oceans, the world of clinical and biomedical research is vast, fast-paced, dynamic and full of unanswered questions. In 2017, numerous advances were made that could change the tide of efforts to fight disease. The Key Advances in Medicine eBook distils the major discoveries made in 2017 and highlights trends to look out for in 2018.

Nature events Directory