PrimeViews

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  • This PrimeView highlights the various subtypes of Castleman disease, a group of lymphoproliferative disorders with shared morphological features but heterogeneous clinical presentation and disease course.

    PrimeView
  • This PrimeView accompanies the Primer article on Essential tremor by Tan and colleagues, and focuses on the epidemiology of this movement disorder.

    PrimeView
  • This PrimeView highlights the pathophysiology of restless legs syndrome, a sleep-related movement disorder that is characterized by an urge to move the legs.

    PrimeView
  • Primary lymphoedema is a condition, often caused by a genetic mutation, characterized by alterations in the structure or function of the lymphatic system.

    PrimeView
  • This PrimeView highlights the epidemiology, diagnosis, pathophysiology and management of Wilms tumour, and summarizes future research needs. It accompanies the Primer on Wilms tumour by Spreafico and colleagues.

    PrimeView
  • Histiocytic disorders are a heterogeneous family of diseases with a wide range of clinical manifestations, from self-resolving skin lesions to multi-organ, life-threatening disease.

    PrimeView
  • This PrimeView highlights the epidemiology, diagnosis and management of membranous nephropathy, and summarizes the mechanisms of this kidney glomeruli autoimmune disease. It accompanies the Primer on membranous nephropathy by Ronco and colleagues.

    PrimeView
  • This PrimeView describes the epidemiology, pathophysiology, diagnosis and management of Behçet syndrome, as well as highlighting patient quality of life and avenues for future research.

    PrimeView
  • This PrimeView highlights the diagnosis and prevention of cholangiocarcinoma, and summarizes its epidemiology, mechanisms, management and outlook. It accompanies the Primer on cholangiocarcinoma by Brindley and colleagues.

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  • This PrimeView highlights the clinical presentations of Marfan syndrome, a genetic disorder caused by pathogenetic variants in FBN1, encoding the extracellular matrix protein fibrillin-1.

    PrimeView
  • This illustrated PrimeView highlights the mechanisms of cutaneous T cell lymphoma, and accompanies the Primer article by Dummer and colleagues.

    PrimeView
  • Psoriatic arthritis is a chronic immune-mediated disease with heterogeneous clinical features. This PrimeView highlights the mechanisms of psoriatic arthritis and accompanies the Primer article by Fitzgerald and colleagues.

    PrimeView
  • A non-union bone fracture represents a chronic medical condition affecting an individual’s psychosocial and economic wellbeing. This PrimeView discusses the epidemiology, pathophysiology and diagnosis of non-union as well as highlights its management and the patient quality of life.

    PrimeView
  • This PrimeView highlights the pathophysiological factors of gastro-oesophageal reflux disease, and summarizes the epidemiology, diagnosis and management of this disorder.

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  • This PrimeView highlights the pathophysiology of acute kidney injury, and summarizes the epidemiology, diagnosis and management of this disease. It accompanies the Primer on this topic by Kellum and colleagues.

    PrimeView
  • This PrimeView highlights the mechanisms of psychopathy, a personality disorder that is characterized by affective, interpersonal, lifestyle and antisocial features.

    PrimeView
  • This PrimeView highlights the steps in the coagulation cascade that are impaired in haemophilia, a disorder caused by mutations in the genes encoding coagulation factors VIII or IX.

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  • This PrimeView accompanies the Primer by Pober, Kozel and colleagues and highlights the epidemiology, pathophysiology, diagnosis, screening, management and quality of life of individuals with Williams syndrome.

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  • Microscopic colitis (MC) is an inflammatory bowel disease that causes persistent watery diarrhoea. This PrimeView highlights the epidemiology, mechanisms, diagnosis and management of MC.

    PrimeView